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hpv33 dna in premalignant and malignant breast lesions in chinese and japanese populations.the relationship between human papillomavirus (hpv) infection and breast cancer is controversial. in this study, paraffin-embedded tissue blocks prepared from 72 patients with benign, premalignant or malignant mammary lesions were randomly collected from the shanghai region of china and tokushima in japan. dna specimens extracted from all tissues were amplified by the polymerase chain reaction (pcr) using hpv16, 18 and 33 primers. southern blot hybridization showed 19 cases to be positive for hp ...199910697510
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