| [investigation of infection with human papillomavirus in areas of high and low incidences of cervical carcinoma in sichuan province]. | from jan. to oct. 1989, we investigated the role of various life style and dietary factors in areas of high and low incidences of cervical carcinoma, as well as infection with types 16 and 33 of human papillomavirus (hpv) in populations. the polymerase chain reaction (pcr) technique was used to detect the infection with hpv 16/33. the result showed that the infection rate of hpv was about 17.9% (guangyuan, area of high incidence of cervical cancer), and the infection rate about 3.4% (mian zhu, a ... | 1992 | 1338628 |
| human papillomavirus types 16 and 33, herpes simplex virus type 2 and other risk factors for cervical cancer in sichuan province, china. | cancer of the cervix is relatively common in china, but has been investigated epidemiologically in only a few studies. in the hospital-based case-control study reported here, we investigated the role of various lifestyle and dietary factors, as well as infection with human papillomavirus (hpv) types 16 and 33 and herpes simplex virus type 2 in the aetiology of invasive cervical cancer. the study was conducted in sichuan province, and involved 101 cases with histologically-confirmed cervical canc ... | 1991 | 1848537 |
| prevalence of hpv infection in esophageal squamous cell carcinoma in chinese patients and its relationship to the p53 gene mutation. | human papillomavirus (hpv), in particular types 16 and 18, is positively associated with anogenital cancers and may be an important etiologic factor in their pathogenesis. the goal of our study was to investigate the role of hpv infection in the pathogenesis of esophageal squamous cell carcinoma (escc) and its relationship with the p53 mutation. we have examined escc collected from sichuan, china, for the presence of hpv infection and p53 mutation. the presence of hpv dna was detected by pcr-sou ... | 1997 | 9378558 |
| analysis of mutations in the urr and e6/e7 oncogenes of hpv 16 cervical cancer isolates from central china. | high rates of cervical cancer have been reported from parts of china and this may reflect a predominance of cervical infection with particularly aggressive human papillomavirus (hpv) variants. this pcr-based investigation of cervical tumours from sichuan province in central china demonstrated an hpv positivity rate of 88%. hpv 16 was most common (21/34, 61%), followed by hpv 18 (3/34, 9%), while types 33, 45, 58 and 59 were each identified in one specimen. sequencing of up to 1349 bases of the 2 ... | 2000 | 10797293 |
| prevalence of human papillomavirus in cervical cancer: a multicenter study in china. | a large-scale epidemiologic survey on the prevalence of different types of human papillomavirus (hpv) in cervical cancer in china is indicated because of the implications for the development of diagnostic probes and vaccines against cervical cancer. a total of 809 cervical cancer specimens were collected from 5 regions in china including shanghai, guangzhou, sichuan, beijing and hong kong. hpv dna was detected in 83.7% of the specimens. hpv-16 was present in 79.6%, hpv-18 in 7.5%, hpv-52 in 2.6% ... | 2002 | 12115548 |
| human papillomavirus infection and loss of heterozygosity in esophageal squamous cell carcinoma. | the incidence/mortality rates of esophageal squamous cell carcinoma (escc) vary widely in different parts of china. human papillomavirus (hpv) infection is considered a possible risk factor. loss of heterozygosity (loh) analysis on 87 escc specimens collected from three different areas of china showed lower frequency of loh at marker d3s1621 in linxian, an area with exceptionally high incidence of escc but low hpv infection rate. hpv-positive escc from hong kong, but not sichuan, had higher freq ... | 2004 | 15327839 |
| hpv prevalence, e6 sequence variation and physical state of hpv16 isolates from patients with cervical cancer in sichuan, china. | infection with high-risk human papillomavirus (hr-hpv) is an important factor associated with cervical cancer. the genetic mutation of hpv16 e6 and integration of hpv16 dna in the cervical carcinoma tissues are considered important genetic changes in cervical lesion progression. but the studies of hr-hpv epidemiology are relatively less in the area of sichuan, china. therefore, we investigated the prevalence of 9 high-risk subtypes and analyzed the genetic mutation characteristic of hpv16 e6 and ... | 2007 | 16970982 |
| evaluation of high-risk human papillomaviruses type distribution in cervical cancer in sichuan province of china. | infection with high-risk human papillomavirus is an important factor associated with cervical cancer, and the distribution of hpv types varies greatly worldwide. determination of type-specific hpv prevalence constitutes an important step towards the development of vaccines for the prevention of cervical cancer. | 2008 | 18644159 |
| the prevalence of sexually transmitted and other lower reproductive tract infections among rural women in sichuan province, china. | to estimate the prevalence of sexually transmitted infections (sti) and lower reproductive tract infections (rti) and determine risk factors for sti among rural women in sichuan province, china, a cross-sectional, community-based cluster sample of 2,000 rural, married women were interviewed, examined and clinical specimens collected to assess for six sti and two non-sexually transmitted rti. the overall prevalence of any sti was 10.9% (95% ci 9.5-12.3); of any sti or rti was 30.8% (95% ci 28.7-3 ... | 2009 | 19842387 |
| phylogeographic analysis of human papillomavirus 58. | human papillomavirus 58 (hpv58) is one type of hpv with high risk of causing cervical cancer. unusually high prevalence of hpv58 has been reported in asia, africa and some other areas. however, due to the scattered distribution of global data, in addition to the lack of data of some hpv58 high-incidence nations and regions, like mainland china, a comprehensive analysis of the global geographical distribution of hpv58 remains blank so far. in this study, hpv58 from the human cervical cancer tissu ... | 2009 | 20016974 |
| prevalence and genotype distribution of human papillomavirus in women with cervical cancer or high-grade precancerous lesions in chengdu, western china. | to study the prevalence and genotype distribution of human papillomavirus (hpv) among women with cervical cancer or high-grade squamous intraepithelial lesions (hsil) in western china. | 2010 | 21092957 |
| variation of human papillomavirus 16 in cervical and lung cancers in sichuan, china. | although the crucial role of human papillomaviruses (hpvs), especially hpv-16 in various cancers has been confirmed, the variation of hpv-16 among different cancers have not been investigated in a specific geographic location. in order to elucidate whether similar hpv-16 variants are involved in different kinds of cancers in the same geographic location, the analysis of sequence variants of e6 and e7 oncogenes and l1 gene of hpv-16 in cervical and lung cancers in sichuan, china, was carried out. ... | 2010 | 21175246 |
| stability study of cervical specimens collected by swab and stored dry followed by human papillomavirus dna detection using the cobas 4800 test. | safer, more convenient methods for cervical sample collection and storage are necessary to facilitate human papillomavirus (hpv) dna testing in low-resource settings. our study aimed to evaluate the stability of cervical specimens collected with dry swabs and stored dry, compared to liquid-based cytology (lbc) samples, as detected by hpv dna testing. women with abnormal cytological findings or hpv-positive results at colposcopy were recruited from the west china second university hospital, sichu ... | 2017 | 27927922 |
| lineage distribution and e2 sequence variation of high-risk human papillomavirus types isolated from patients with cervical cancer in sichuan province, china. | to explore the nucleotide sequence variability of the e2 gene in high-risk hpv types in cervical cancer patients from sichuan province, china, the e2 genes of eight high-risk hpv types were amplified and sequenced. several novel nucleotide substitutions and deletions were observed. the lineages to which the isolates belonged were determined by phylogenetic analysis, employing the sequence of the representative lineages/sublineages in the coherent classification and nomenclature system as referen ... | 2015 | 26303138 |
| [relationship of human papillomavirus subtypes and multiple infection with different cervical precancerous diseases in sichuan province]. | to investigate the relationship of human papillomavirus (hpv) subtypes and multiple infections with different cervical precancerous diseases. | 2015 | 26121866 |