| polymorphism at codon 72 of p53, human papillomavirus, and cervical cancer in south india. | it has been suggested that host genetic factors play a role in human papillomavirus (hpv)-associated tumorigenesis, although the issue continues to be a focus of much debate. previous studies have reported that a common polymorphism of the wild type p53 gene at codon 72 of exon 4 (arg/arg) is associated with a sevenfold increased risk of hpv-associated cancer compared to arg/pro and pro/pro polymorphisms. in vitro studies also suggested that the arg/arg polymorphism was much more susceptible to ... | 2002 | 12458344 |
| accuracy of human papillomavirus testing in primary screening of cervical neoplasia: results from a multicenter study in india. | the knowledge that cervical neoplasia are caused by human papillomavirus (hpv) infection has led to the evaluation of its role in screening. we evaluated the accuracy of hpv testing by hybrid capture ii (hc ii) method in detecting cervical intraepithelial neoplasia grade 2 and 3 (cin 2 and 3) lesions in 4 cross-sectional studies with common protocol and questionnaire in 3 different locations (kolkata, mumbai and trivandrum) in india. these studies involved 18,085 women aged 25-65 years. the refe ... | 2004 | 15352050 |
| cervical and oral cancer screening in india. | incidence of both cervical and oral cancer are high in india. although there are no organized cervical or oral screening programmes in the country, a number of research projects are ongoing or recently completed. in cervical screening, a number of studies of visual inspection with various aids and studies of human papillomavirus (hpv) testing are in progress. long-term follow-up of these will inform policy on cervical screening in limited resource countries. a randomized trial of oral visual ins ... | 2006 | 17227640 |
| region-wise distribution of high-risk human papillomavirus types in squamous cell carcinomas of the cervix in india. | assessment of the prevalence and type distribution of human papillomavirus (hpv) in squamous cell carcinomas (scc) of the cervix across india was undertaken to estimate the impact of available prophylactic hpv-l1 vaccines in the country and to find out additional types that might be needed to be incorporated in second-generation vaccines. | 2010 | 20683415 |
| no role for human papillomavirus infection in oral cancers in a region in southern india. | oral cancer is a major public health issue in india with ∼ 77,000 new cases and 52,000 deaths yearly. paan chewing, tobacco and alcohol use are strong risk factors for this cancer in india. human papillomaviruses (hpvs) are also related to a subset of head and neck cancers (hncs). we examined the association between oral hpv and oral cancer in a sample of indian subjects participating in a hospital-based case-control study. we recruited incident oral cancer cases (n = 350) and controls frequency ... | 2016 | 26317688 |