| high-risk human papillomavirus types in cytologically normal cervical scrapes from kenya. | seventy-seven women with normal cervical cytology on routine visit to a family planning clinic in nairobi, kenya, were analysed for genital human papillomavirus (hpv) types by polymerase chain reaction (pcr). we applied a general primer pair (gp60/gp124) recognising sequences conserved among hpv types 6, 11, 16, 18, 31 and 33. of the 77 specimens tested 15 (19.5%) proved to be positive for genital hpv. amplification products were examined for the presence of high-risk hpv types by slot-blot hybr ... | 1992 | 1312661 |
| human immunodeficiency virus, human papillomavirus, and cervical intraepithelial neoplasia in nairobi prostitutes. | to evaluate the impact of human immunodeficiency virus (hiv) on human papillomavirus (hpv) and cervical intraepithelial neoplasia (cin), a study was conducted of 147 hiv-seropositive and 51 hiv-seronegative prostitutes in nairobi, kenya. among the women infected with hiv, 10 (7%) had signs or symptoms of significant hiv-related disease, and the remaining 93% were asymptomatic. the prevalence of cervical hpv dna was 37% among hiv-seropositive women and 24% in hiv-seronegative women (odds ratio [o ... | 1992 | 1313992 |
| cervical cancer screening and detection of genital hpv-infection and chlamydial infection by pcr in different groups of kenyan women. | a pilot study was conducted in nairobi, kenya, to evaluate the feasibility of a larger study on the prevalence of cervical cancer and precancerous lesions and on the role of sexually transmitted diseases (std) as risk factors for cervical cancer in kenya. 692 women were screened for cervical cancer by cytology in 3 city commission family planning clinics and in 1 city commission std referral clinic in nairobi. in one family planning clinic and in the std clinic, a sample of the participating wom ... | 1992 | 1567270 |
| risk factors for human papillomavirus and cervical precancerous lesions, and the role of concurrent hiv-1 infection. | to identify risk factors for human papillomavirus (hpv) infection and squamous intraepithelial lesions (sil) of the cervix, and to measure the impact of concurrent hiv-1 infection. | 1999 | 10405062 |
| distribution of human papillomavirus in a family planning population in nairobi, kenya. | in sub-saharan africa, cervical cancer is the leading cancer among women. the causative role of different human papillomavirus (hpv) types in cervical cancer is established, but the distribution of hpv types within this region is largely unknown. | 2003 | 12567172 |
| comparison of pap smear, visual inspection with acetic acid, human papillomavirus dna-pcr testing and cervicography. | to assess the test qualities of four screening methods to detect cervical intra-epithelial neoplasia in an urban african setting. | 2005 | 15847874 |
| human papillomavirus types in women with invasive cervical carcinoma by hiv status in kenya. | to evaluate the fraction of invasive cervical carcinoma (icc) that could be prevented in hiv-infected women by vaccines currently available against human papillomavirus (hpv)16 and 18, we conducted a cross-sectional study in women with icc in nairobi, kenya. fifty-one hiv-positive women were frequency-matched by age to 153 hiv-negative women. cervical cells were tested for hpv dna using polymerase chain reaction-based assays (spf10-inno-lipa). comparisons were adjusted for multiplicity of hpv ty ... | 2008 | 17764116 |
| human papillomavirus infection and cervical abnormalities in nairobi, kenya, an area with a high prevalence of human immunodeficiency virus infection. | human papillomavirus (hpv) infection and cervical abnormalities, and their association with human immunodeficiency virus (hiv) infection were studied in 488 women who visited a health center in nairobi. pcr-based hpv and cervical cytology tests were carried out on all participants, and peripheral cd4+ t cells and plasma hiv rna were quantitated in hiv positive women. hiv were positive in 32% (155/488) of the women; 77% of these were untreated, and the others had been treated with anti-retroviral ... | 2008 | 18360898 |
| prevalence of human papillomavirus genotypes in hiv-1-infected women in seattle, usa and nairobi, kenya: results from the women's hiv interdisciplinary network (whin). | hiv-infected women have a high prevalence of human papillomavirus (hpv) infection and are more likely to be infected with hpv genotypes that are considered high-risk and have the potential for progressing to cervical cancer. the currently available hpv vaccines protect against specific hpv genotypes that may not be the most important causes of dysplasia and potentially of cervical cancer in hiv-1-infected women. african women have been underrepresented in the studies of global prevalence of hpv ... | 2010 | 20655263 |
| clinical characteristics associated with mycoplasma genitalium among female sex workers in nairobi, kenya. | the prevalence of mycoplasma genitalium is high in vulnerable populations of women in low-resource settings. however, the epidemiology of infection in these populations is not well established. to determine the prevalence of mycoplasma genitalium and its association with cervical cytology and other correlates, we recruited 350 female sex workers (fsw) who were 18 to 50 years old in nairobi, kenya, for a cross-sectional study. a questionnaire was administered at baseline to obtain information on ... | 2014 | 25100823 |
| the role of chlamydia trachomatis in high-risk human papillomavirus persistence among female sex workers in nairobi, kenya. | little is known about risk factors for persistent high-risk human papillomavirus (hrhpv) infection in low-income settings, and prior research has not quantified the relative duration of hrhpv infections stratified by risk factors. we compared the duration of hrhpv infection among female sex workers (fsws) by exposure to sexually transmitted infections (stis), using a highly sensitive biomarker assay. | 2015 | 25970306 |
| high-risk human papillomavirus messenger rna testing in physician- and self-collected specimens for cervical lesion detection in high-risk women, kenya. | little is known about the performance of physician-versus self-collected specimens for high-risk human papillomavirus (hrhpv) messenger rna (mrna) testing or risk factors for hrhpv mrna positivity in physician- versus self-collected specimens. we compared the performance of hrhpv mrna testing of physician- and self-collected specimens for detecting cytological high-grade squamous intraepithelial lesions or more severe (≥hsil) and examined risk factors for hrhpv mrna positivity in female sex work ... | 2013 | 23965776 |
| multiple human papillomavirus infections and hiv seropositivity as risk factors for abnormal cervical cytology among female sex workers in nairobi. | we estimated type-specific prevalence of human papillomavirus (hpv) and examined risk factors for abnormal cervical cytology among 296 female sex workers from nairobi, kenya. over half (54%) were infected with a high-risk (hr) hpv type, of which hpv16 and 52 were the most common types. hiv-1 prevalence was 23% and hiv-1 sero-positivity was associated with high-grade cervical lesions, particularly among women with cd4 count less than 500 cells/mm(3) (odds ratio [or] = 6.9; 95% confidence interval ... | 2013 | 23535357 |
| comparison of hpv dna testing in cervical exfoliated cells and tissue biopsies among hiv-positive women in kenya. | hiv-positive women are infected with human papillomavirus (hpv) (especially with multiple types), and develop cervical intraepithelial neoplasia (cin) and cervical cancer more frequently than hiv-negative women. we compared hpv dna prevalence obtained using a gp5+/6+ pcr assay in cervical exfoliated cells to that in biopsies among 468 hiv-positive women from nairobi, kenya. hpv prevalence was higher in cells than biopsies and the difference was greatest in 94 women with a combination normal cyto ... | 2013 | 23444059 |