| human papillomavirus (hpv) infection, hiv infection and cervical cancer in tanzania, east africa. | the presence of hpv-dna was determined in tumor biopsies of cervical-cancer patients and in cervical swabs of non-cancer patients from tanzania, east africa, by southern blot hybridization and/or pcr. hpv types 16 and 18 were detected in 38% and 32%, respectively, of 50 cervical-carcinoma biopsies. a consensus primer pcr capable of detecting a broad spectrum of hpv types revealed the presence of hpv-dna in 59% of 359 cervical swabs of non-cancer patients. type-specific pcr showed that types 16 a ... | 1992 | 1318265 |
| high frequency of human papillomavirus 6/11, 16, and 18 infections in precancerous lesions and squamous cell carcinoma of the conjunctiva in subtropical tanzania. | dysplastic lesions and epithelial neoplasms of the conjunctiva account for approximately 2% of all malignant tumors in subtropical tanzania. we examined the pathophysiologic role of human papillomavirus (hpv) in the development of conjunctival carcinoma in subtropical tanzania, which has a high hpv prevalence. tissue samples from 14 patients were obtained from the cancer registry archives at the medical center of the university in dar es salaam, tanzania. a highly sensitive nonradioactive in sit ... | 2004 | 15539387 |
| association between invasive cancer of the cervix and hiv-1 infection in tanzania: the need for dual screening. | cancer of the cervix is the second commonest malignancy in females worldwide and is the leading malignancy among women in tanzania. cancer of the cervix has been strongly associated with human papilloma virus (hpv) which is a sexually transmitted disease. however, the role of hiv-1 in the aetiology of cancer of the cervix is less clear. studies suggest that hpv and hiv-1 infection are synergistic and therefore their dual occurrence may fuel increased incidence of cancer of the cervix and aids. w ... | 2008 | 18664298 |
| risk factors for hiv positivity among more than 3,400 tanzanian women. | in a cross-sectional study of 3,424 women from urban (dar es salaam) and rural (pwani, mwanza, and mtwara) tanzania, conducted in 2008-2009, we investigated risk factors for human immunodeficiency virus (hiv) and the association between different measures of human papillomavirus (hpv) and hiv positivity. study participants were interviewed about socio-demographic and reproductive factors and sexual behavior. blood samples were tested for hiv, and the women underwent a gynecological examination. ... | 2016 | 27379612 |
| prevalence and risk factors of cervical squamous intraepithelial lesions among hiv-infected women in dar es salaam, tanzania. | to determine the prevalence and predictors of cervical squamous intraepithelial lesions (sil) among hiv-infected women in tanzania, a cross-sectional study was conducted among hiv-infected women at hiv care and treatment clinics. a papanicolaou (pap) smear was used as a screening tool for detection of cervical sil. from december 2006 to august 2009, 1365 hiv-infected women received cervical screening. the median age was 35 (interquartile range [iqr]: 30-42) years, and the median cd4 + cell count ... | 2016 | 25957324 |
| performance of visual inspection with acetic acid and human papillomavirus testing for detection of high-grade cervical lesions in hiv positive and hiv negative tanzanian women. | the aim of this cross sectional study was to assess type distribution of human papillomavirus (hpv) among hiv positive and hiv negative women who underwent cervical cancer screening, and to examine the ability of visual inspection with acetic acid (via), the standard detection method in tanzania, and hpv-testing to detect cytologically diagnosed high grade lesions or cancer (hsil+). women from different areas in tanzania were invited by public announcement to cervical cancer screening organized ... | 2014 | 24391021 |