antigenic and genetic characterization of bordetella pertussis recovered from quebec, canada, 2002-2014: detection of a genetic shift.despite vaccination, cyclical peaks of bordetella pertussis incidence rates are still observed in canada and other developed countries, making pertussis one of the most prevalent vaccine preventable bacterial diseases. in the postacellular vaccine era, evolution of bacterial strains has resulted in strains with altered vaccine antigens. previous canadian studies have focused on isolates mainly from the provinces of ontario and alberta, with only small numbers of isolates from other provinces. th ...201626910633
strain variation among bordetella pertussis isolates from québec and alberta provinces of canada from 1985 to 1994.pulsed-field gel electrophoresis and gene typing were able to differentiate among 3,597 bordetella pertussis isolates circulating in alberta and québec provinces, canada, from 1985 to 1994 and distinguish them from the strains used in vaccine production. this study provides a baseline for continued surveillance of prevalent and emerging strains of b. pertussis in canada.200312843089
pertussis resurgence in canada largely caused by a cohort effect.beginning in 1990 canada experienced a resurgence of pertussis. changes in incidence and hospitalization according to age in the province of quebec between 1983 and 1998 were examined to assess the presence of a cohort effect resulting from a poorly protective vaccine.200312544404
characterization of outbreak and vaccine strains of bordetella pertussis--quebec. 19938298581
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