| detection of filaria-specific igg4 antibodies using brugia rapid test in individuals from an area highly endemic for brugia timori. | the filarial parasite brugia timori is of great public health importance in some islands of eastern indonesia. to establish a simple serological test for the identification and post-treatment monitoring of areas endemic for b. timori, a rapid immunochromatographic dipstick test (brugia rapid, br) was evaluated on microfilaraemic and amicrofilaraemic individuals. this test is based on the detection of anti-filarial igg4 antibodies that react with a recombinant brugia malayi antigen (bmr1). in our ... | 2004 | 15099812 |
| high prevalence of brugia timori infection in the highland of alor island, indonesia. | to identify areas endemic for brugia timori infection, a field survey was carried out in 2001 on alor, east nusa tenggara timor, indonesia. elephantiasis was reported on this island by villagers as a major health problem. bancroftian filariasis was detected in four villages in the coastal area, whereas b. timori was identified in four rice-farming villages. no mixed infections with both species were found. in the highland village mainang (elevation = 880 m), 586 individuals were examined for b. ... | 2002 | 12201590 |
| microfilarial periodicity analysis of the survey data from six localities in indonesia. | the survey data of microfilarial periodicity of 2 species of filariae brugia malayi at 4 localities, mahang and lampihong in south kalimantan, bengkulu in south sumatra, palolo in central sulwesi, and the species of brugia timori at 2 localities, flores and alor islands in nusa tenggara were analysed by using aikat and das's modified statistical method. nine cases at mahang and five cases at lampihong were recognized as same group of non-periodic b. malayi and 1 case at mahang was considered to ... | 1979 | 483016 |
| pcr-based detection and identification of the filarial parasite brugia timori from alor island, indonesia. | brugia timori is widely distributed on alor island, indonesia, where it causes a high degree of morbidity. the hhai tandem repeat of b. timori was found to be identical to that of b. malayi, for which sensitive pcr-based assays have already been developed. using one of these assays, a single microfilaria (mf) of b. timori, present in a spot of dry blood on filter paper, could be detected. the assay was equally sensitive in the detection of b. timori and b. malayi. when the collected mosquitoes w ... | 2002 | 12625936 |
| treatment of brugia timori and wuchereria bancrofti infections in indonesia using dec or a combination of dec and albendazole: adverse reactions and short-term effects on microfilariae. | filariasis caused by brugia timori and wuchereria bancrofti is an important public health problem on alor island, east nusa tenggara, indonesia. to implement a control programme, adverse reactions and short-term effects on the microfilaria (mf) density were studied following a divided dose of diethylcarbamazine (dec, 6 mg/kg body weight - 100 mg on day 1 and the rest on day 3) or a single dose of dec (6 mg/kg body weight on day 3) and albendazole (alb, 400 mg). in order to define the most approp ... | 2002 | 12358626 |
| using knowledge, attitudes and practice (kap) surveys on lymphatic filariasis to prepare a health promotion campaign for mass drug administration in alor district, indonesia. | we report the results of two surveys of people's knowledge, attitudes and practices (kap) regarding lymphatic filariasis (lf) in alor district, eastern indonesia. the results of the surveys were used to prepare and evaluate the social mobilization component of a pilot mass drug administration (mda) in five villages. in the study area, the filarial parasites brugia timori and wuchereria bancrofti are highly endemic. frequent and severe adverse reactions after mda may occur especially in areas end ... | 2006 | 17054754 |
| lymphatic filariasis and brugia timori: prospects for elimination. | brugia timori is a pathogenic filarial nematode of humans, replacing the closely related species brugia malayi on some islands in eastern indonesia. recent studies on alor island show that, locally, b. timori is still of great public health importance, causing mainly acute filarial fever and chronic lymphedema. pcr-based assays to detect parasite dna, in addition to assays for detecting specific antibodies that have been originally developed for b. malayi, can be used efficiently as diagnostic t ... | 2004 | 15246315 |