Publications

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relationships between the species of fasciola and their molluscan hosts. 19704934031
some observations on the epidemiology of fascioliasis in relation to the timing of molluscicide applications in the control of the disease. 19715102169
the pathogenesis o fascioliasis. 19665948200
a three-year study of lymnaea truncatula habitats, disease foci of fascioliasis. 19817284746
emergence of fasciolosis in cattle in east anglia.liver fluke (fasciola hepatica) infection caused weight loss, diarrhoea, decreased milk yield and occasionally death in cattle in east anglia during the winters of 2001 to 2003. the condition had previously been limited mainly to stock imported into this part of britain from endemically infected areas. in composite faecal samples collected by 16 farm animal veterinary practices in norfolk, suffolk and essex, fluke eggs were found in 15 (28.8 per cent) of 52 previously unaffected suckler herds an ...200516272544
high incidence of liver fluke in cattle herds in england and wales. 201020643883
fasciola hepatica is associated with the failure to detect bovine tuberculosis in dairy cattle.bovine tuberculosis (btb) is a significant and intractable disease of cattle caused by mycobacterium bovis. in the united kingdom, despite an aggressive eradication programme, the prevalence of btb is increasing with an unexplained, exponential rise in cases year on year. here we show in a study involving 3,026 dairy herds in england and wales that there is a significant negative association between exposure to the common, ubiquitous helminth parasite, fasciola hepatica and diagnosis of btb. the ...201222617293
composite faecal egg count reduction test to detect resistance to triclabendazole in fasciola hepatica.a faecal egg count reduction test, using composite samples, was developed in order to assess the efficacy of the flukicide, triclabendazole (tcbz) on commercial sheep farms in england and wales. first, a comparison between individual counts and composite counts was conducted using sheep on two farms with different levels of infection. faecal samples were collected from 50 sheep on each farm at the time of tcbz treatment and 21 days later. the results showed that a composite fluke egg coun ...201222791519
ostertagia spp., rumen fluke and liver fluke single- and poly-infections in cattle: an abattoir study of prevalence and production impacts in england and wales.this study aims at investigating the occurrence, risk factors and production impacts on beef carcass parameters of three of the most important cattle helminth infections in england and wales. abomasa, reticulorumens and livers from healthy cattle were collected and examined post-mortem quarterly over a one year period in an abattoir in south-west england. specific viscera from 974 cattle were collected, examined and scored for ostertagia spp., adult rumen fluke and liver fluke lesions/presence. ...201627664452
faecal egg count reduction test to detect lack of efficacy of triclabendazole. 201021257517
seroprevalence and spatial distribution of fasciola hepatica-infected dairy herds in england and wales.the seroprevalence of fasciola hepatica infection in a population of commercial dairy herds in england and wales was estimated using an elisa that detected antibodies to f hepatica in bulk tank milk. a total of 3130 milk samples, obtained as convenience samples from two commercial milk-testing laboratories, were tested during the winter of 2006/07. herds considered to be seropositive were categorised as low positive, medium positive or high positive. a geospatial map was drawn to show the distri ...201020472872
the development of linear regression models using environmental variables to explain the spatial distribution of fasciola hepatica infection in dairy herds in england and wales.fasciolosis caused by fasciola hepatica is a major cause of economic loss to the agricultural community worldwide as a result of morbidity and mortality in livestock. spatial models developed with the aid of geographic information systems (gis) can be used to develop risk maps for fasciolosis for use in the formulation of disease control programmes. here we investigate the spatial epidemiology of f. hepatica in dairy herds in england and wales and develop linear regression models to explain obse ...201020227416
hepatic fascioliasis at a london hospital--the importance of recognising typical radiological features to avoid a delay in diagnosis.hepatic fascioliasis is a zoonosis caused by the trematode fasciola hepatica, which can cause hepatobiliary disease in humans via the ingestion of contaminated water or aquatic vegetables. reported cases of human infection with f. hepatica arise in regions where cattle are raised, with particular abundance in south america and the middle east. the typical radiological appearances associated with fascioliasis are well reported and are likely to be more easily recognisable by radiologists in these ...200919729549
prevalence of fasciola hepatica in dairy herds in england and wales measured with an elisa applied to bulk-tank milk.an elisa developed to diagnose fasciola hepatica infection in cattle by detecting serum antibodies was adapted and validated for use with samples of bulk-tank milk. the prevalence of the infection in 61 dairy herds was established by using serum antibody levels or faecal egg counts measured in a proportion of the cows in each herd. the correlation between the results of the elisa and the herd seroprevalence was 0.83. using a cut-off value of 27 per cent positive, the bulk-tank elisa identified h ...200515937238
determination of farm-level risk factors for abnormalities observed during post-mortem meat inspection of lambs: a feasibility study.to investigate the feasibility of using information about the health and management of lambs on farms to predict the risk of gross abnormalities at post-mortem meat inspection, 6732 lambs from 30 different farms in great britain were followed through to slaughter in 1995/6. the farm-level data were collected during farm visits at the beginning of the study. routine meat inspection findings for the lambs were obtained from the 10 participating abattoirs. the most common abnormalities found during ...199910487647
liver fluke in great britain: a survey of affected livers.over a period of 15 months data were collected from abattoirs in great britain on 213,082 cattle and 362,838 sheep livers to determine the distribution and prevalence of damage by fasciola hepatica. the stock came from 8239 farms, and from livestock markets in 81 counties. 53 per cent of the farms had sent affected stock, with significant percentages in eastern as well as the western counties of england and scotland. 21 per cent of all cattle and 7 per cent of all sheep livers examined were affe ...19751202744
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