| cot deaths in birmingham. | the spatial and temporal distributions of cot deaths and of infant respiratory deaths in birmingham between 1964 and 1984 were examined. respiratory deaths declined and cot deaths increased, and the combined rate showed a downward trend. seasonal variations were identical in the two groups and in each case were more powerfully related to date of death than to date of birth. cumulative mortalities were parallel by age, depended crucially upon the quarter of the year in which the child was born, a ... | 1991 | 1958402 |
| a prospective study of viral and mycoplasma infections in chronic inflammatory bowel disease. | seventy-two children with chronic inflammatory bowel disease were investigated for infections with various viruses and mycoplasma pneumoniae, chlamydia psittaci, and coxiella burnetii to determine whether these pathogens are associated with acute onset exacerbations. altogether 54 infections were identified serologically, of which 23 (42.6%) were associated with exacerbations. this corresponded to 24.2% of the recorded exacerbations during the study period. the respiratory pathogens accounted fo ... | 1990 | 2298361 |
| prospective study of the aetiology and outcome of pneumonia in the community. | a prospective one-year study of community pneumonia was conducted in nottingham. 236 of 251 episodes of pneumonia (defined as an acute lower respiratory tract infection, for which antibiotics were prescribed, associated with new focal signs on examination of the chest) were investigated. acute radiographic changes were present in 93 (39%). a pathogen was identified in 129 (55%) episodes, with streptococcus pneumoniae, haemophilus influenzae, and influenza viruses those most frequently identified ... | 1987 | 2882091 |
| whooping cough and unrecognised postperinatal mortality. | trends in postperinatal infant mortality from respiratory causes and the sudden infant death syndrome in england and wales for 1968 to 1984 were examined. these were compared by time series analysis with changes in the incidence of specific infective diseases and organisms for the same period. discontinuity was found in association with the occurrence of whooping cough between 1977 and 1982. associations with the general incidence of respiratory infections and other specific organisms were less ... | 1988 | 3126714 |
| adult community-acquired pneumonia in central london. | strep. pneumoniae was diagnosed as the cause of pneumonia in 40 (50%) of 80 consecutive adults admitted to st stephen's hospital with community-acquired pneumonia. none of the patients had evidence of mycoplasma pneumoniae infection, and legionella pneumophila serology was positive on only one occasion. in 29 patients (36%) no causative organism was demonstrated. the diagnosis of pneumococcal infection was obtained in 15 cases by isolating strep. pneumoniae from the sputum, in 13 further cases b ... | 1984 | 6747977 |
| causes of pneumonia presenting to a district general hospital. | the incidence of bacterial, viral, mycoplasma, and rickettsial infections has been assessed prospectively in 210 adult patients with pneumonia who presented to a district hospital over a six-year period. one hundred and thirteen infective agents were detected in 103 patients. the agent most frequently detected was mycoplasma pneumoniae which accounted for 30 infections. a bacterial pathogen was found in 43 patients. streptococcus pneumoniae was the most common of these (24 patients); staphylococ ... | 1981 | 7314031 |
| the etiology of community-acquired pneumonia among hospitalized patients during a chlamydia pneumoniae epidemic in finland. | the etiology of community-acquired pneumonia during a chlamydia pneumoniae epidemic was studied among 125 hospitalized patients. etiologic investigations included blood and sputum cultures, pneumococcal antigen detection, and serologic investigations for common respiratory viruses and for streptococcus pneumoniae, haemophilus influenzae, moraxella catarrhalis, mycoplasma pneumococcal antigen detection, and serologic investigations for common and for streptococcus pneumoniae, haemophilus influenz ... | 1995 | 7594672 |
| prospective study of aetiology and outcome of adult lower-respiratory-tract infections in the community. | community-acquired adult lower-respiratory-tract infections (lrti) are generally thought to be caused by atypical and viral infections. we have studied 480 adults presenting to a single general practice with community-acquired lrti between november, 1990, and december, 1991. the overall incidence was 44 cases per 1000 population per year; the incidence was 2-4 times higher in people aged 60 and over than in those aged less than 50. 206 patients were studied in detail; among this group 91 (44%) h ... | 1993 | 8094769 |
| acute viral infections of upper respiratory tract in elderly people living in the community: comparative, prospective, population based study of disease burden. | to evaluate the disease burden of upper respiratory infections in elderly people living at home. | 1997 | 9366736 |
| influenza a community-acquired pneumonia in east london infants and young children. | community-acquired pneumonia (cap) is common in young children, but there are few data in europe on influenza a virus as a cause of childhood cap. the aim of this study was to determine the relative contributions of different etiologic agents to cap in children. | 2003 | 14551480 |
| detection of simkania negevensis by culture, pcr, and serology in respiratory tract infection in cornwall, uk. | respiratory tract infections are often treated empirically without investigation to detect the aetiological agent, which may be a virus or a bacterium, including atypical pathogens such as chlamydophila pneumoniae or mycoplasma pneumoniae. recently, several types chlamydia-like intracellular bacteria have been detected in environmental samples and clinical specimens. little is known of their geographical distribution and potential pathogenicity. we describe the detection, by pcr and isolation in ... | 2006 | 16505289 |
| influenza, campylobacter and mycoplasma infections, and hospital admissions for guillain-barré syndrome, england. | guillain-barré syndrome (gbs) is the most common cause of acute flaccid paralysis in polio-free regions. considerable evidence links campylobacter infection with gbs, but evidence that implicates other pathogens as triggers remains scarce. we conducted a time-series analysis to investigate short-term correlations between weekly laboratory-confirmed reports of putative triggering pathogens and weekly hospitalizations for gbs in england from 1993 through 2002. we found a positive association betwe ... | 2006 | 17326939 |
| ten years of viral and non-bacterial serology in adults with cystic fibrosis. | viral infections are associated with pulmonary exacerbations in children with cystic fibrosis (cf), but few studies have addressed the frequency in adults. this paper investigates the frequency and impact of viral infections in adults with cf receiving intravenous antibiotics. pre- and post-treatment spirometry, inflammatory markers and antibody titres against influenza a, influenza b, adenovirus, respiratory syncytial virus, mycoplasma pneumoniae, chlamydia psittaci, and coxiella burnetti were ... | 2008 | 17352838 |
| prevalence of mycoplasma encephalitis. | | 2011 | 21616452 |
| Mycoplasma pneumoniae and respiratory virus infections in children with persistent cough in England: a retrospective analysis. | Persistent cough following an acute respiratory tract infection is common in children, but clinicians may find it difficult to give accurate prognostic information on likely duration of cough without a microbiologic diagnosis. This study estimates the prevalence of Mycoplasma pneumoniae (Mp) and assesses the prognostic value of detecting Mp and respiratory viruses in children with persistent cough. | 2011 | 21857262 |
| mycoplasma pneumoniae in elderly patients with stroke. a case-control study on the seroprevalence of m. pneumoniae in elderly patients with acute cerebrovascular disease - the m-peps study. | previous studies have suggested certain infections as potential risk factors for stroke. chlamydia pneumoniae, an atypical respiratory pathogen, has been linked to atherosclerotic vascular diseases. mycoplasma pneumoniae, another atypical respiratory micro-organism, can rarely cause stroke. we investigated whether serological markers of m. pneumoniae infection were associated with acute stroke or transient ischaemic attack (tia) in elderly patients. | 2004 | 15026614 |
| is mycoplasma pneumonia associated with childhood acute lymphoblastic leukemia? | acute lymphoblastic leukemia (all) in the childhood peak may be a rare response to delayed first exposure to one or more common infectious agent(s). mycoplasma pneumonia has the appropriate socioeconomic correlates and clinical symptoms and the hypothesis that delayed first exposure to it may contribute to all is considered. counts of positive reports of m pneumonia from disease surveillance data for england and wales (united kindom) for 1975-92 have been taken as proxies for community burden of ... | 1997 | 9328203 |
| studies on an epidemic of respiratory disease caused by mycoplasma pneumoniae. | | 1967 | 6017522 |
| antibody to mycoplasma pneumoniae in normal subjects and in patients with chronic bronchitis. | | 1968 | 5250129 |
| surveillance of mycoplasma pneumoniae infections in scotland 1986-1991. | mycoplasma pneumoniae is the second most common cause of community-acquired pneumonia. infection is found worldwide and epidemics are said to occur in 4-yearly cycles. in scotland this pattern has been noted since 1982 and, in common with england and wales as well probably as other parts of europe, there is a current epidemic which began in the autumn of 1990. the disease has been noted predominantly in children and young adults, with lower respiratory tract infection as the most common manifest ... | 1992 | 1431178 |
| a general practice survey of the incidence of mycoplasma pneumoniae infections. | an epidemiological survey was carried out at two centres in the north of england (liverpool and sunderland). one hundred and twenty patients were included in this survey to determine the relative incidence of mycoplasma pneumoniae infections in patients who present to their physician with an acute lower respiratory tract infection. data were available at the end of the survey in 115 patients. only one patient had a positive test for m.pneumoniae. there were nine patients who had a positive antib ... | 1976 | 955701 |
| epidemiology of mycoplasma pneumoniae infection in the united kingdom: an analysis of reports to the public health laboratory service of england and wales. | infection with mycoplasma pneumoniae appears to follow a cyclic pattern in the united kindom, with periods of increased prevalence lasting about two years. outbreaks occurred in 1971-1972 and 1974-75, and probably also in 1967-68. infection confirmed by laboratory tests appeared to be commonest in older children, especially those aged 5-14, and least common in adults over 65 years of age. lower respiratory tract infection was the clinical feature most frequently reported. | 1976 | 955698 |
| mycoplasma pneumoniae infections in children. | details are given of all serologically confirmed mycoplasma pneumoniae infections in children referred to bristol hospitals during an epidemic lasting 18 months. 44 children, many below school age, had lower respiratory infections. the majority had cough and malaise which had failed to respond to antibiotics given before referral. chest x-rays showed no pathognomonic features: segmental or patchy consolidation was common; 3 cases of lobar consolidation. cold agglutinins were raised in 9 out of 1 ... | 1978 | 626517 |
| the treatment of mycoplasma pneumoniae infections. | | 1977 | 601554 |
| increased detection of mycoplasma pneumoniae infection in children in england and wales, october 2011 to january 2012. | | 2012 | 22340973 |
| comparative genome analysis of mycoplasma pneumoniae. | mycoplasma pneumoniae is a common pathogen that causes upper and lower respiratory tract infections in people of all ages, responsible for up to 40% of community-acquired pneumonias. it also causes a wide array of extrapulmonary infections and autoimmune phenomena. phylogenetic studies of the organism have been generally restricted to specific genes or regions of the genome, because whole genome sequencing has been completed for only 4 strains. to better understand the physiology and pathogenici ... | 2015 | 26275904 |
| detection of macrolide resistant mycoplasma pneumoniae in england, september 2014 to september 2015. | mycoplasma pneumoniae infection can cause pneumonia, particularly in children. global increase in macrolide-resistant m. pneumoniae is of concern due to limited therapeutic options. we describe the detection of macrolide resistance-conferring mutations in 9.3% of 43 clinical specimens where m. pneumoniae was detected in england and wales from september 2014‒september 2015. this study aims to impact by highlighting the presence of macrolide resistance in m. pneumoniae positive patients, promoting ... | 2015 | 26675545 |
| increased incidence of mycoplasma pneumoniae infection in england and wales in 2010: multiocus variable number tandem repeat analysis typing and macrolide susceptibility. | | 2011 | 21596009 |
| mycoplasma pneumoniae infection in primary care investigated by real-time pcr in england and wales. | real-time pcr was employed to detect a conserved region of the p1 cytadhesin gene of mycoplasma pneumoniae in combined nose and throat swabs collected from patients attending gp surgeries during 2005-2009 with symptoms of respiratory tract infection (rti). samples were collected as part of an annual winter epidemiological and virological linked study in england and wales. a total of 3,987 samples were tested, 65 (1.7%, 95%ci 1.3-2.1) had detectable m. pneumoniae dna. positive patients were detec ... | 2011 | 21311941 |