Publications

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new and old agents in diarrhea: a prospective study of an indigenous adult african population.we conducted a prospective study 77 indigenous african adults with acute diarrhea seeking care at the major hospital in nairobi, kenya, to determine the major pathogens responsible for this syndrome in adults. fecal and blood specimens were collected and examined for enteric bacterial pathogens, viruses, and parasites. in 13 (26%) inpatients and 11 (49%) outpatients shigella was found, and heat-labile and heat-stable forms of enterotoxigenic escherichia coli were found in 9 (18%) inpatients and ...1978209697
comparison of four nitroimidazole compounds for treatment of symptomatic amoebiasis in kenya.four antiamoebic drugs currently used in many kenyan hospitals and health centres were compared for their efficacy on symptomatic luminal amoebiasis in kiambu, kilifi, and machakos hospitals during this study. the drugs were; the brand metronidazole (flagyl, may & baker, kenya ltd.), the generic metronidazole (metrozol, cosmos ltd., nairobi, kenya), the brand tinidazole (fasigyn, pfizer laboratories ltd.) and the generic tinidazole (tynazole laboratory and allied equipments, kenya ltd). clinical ...19892606014
antibodies against entamoeba histolytica in human milk and serum in kenya.a modified enzyme-linked immunosorbent assay (elisa) technique has been developed for the detection of secretory immunoglobulin a (siga) antibodies against entamoeba histolytica. by substituting phosphate-buffered saline-triton for phosphate-buffered saline-tween as the antibody incubating buffer, unspecific absorption of siga was avoided. as revealed by chessboard titrations, the optimal amount of antigen for coating was higher in siga than in igg elisa. a purified antigen from the membrane pel ...19836306046
intestinal parasitic infections in children presenting with diarrhoea in outpatient and inpatient settings in an informal settlement of nairobi, kenya.the distribution of and factors associated with intestinal parasitic infections are poorly defined in high risk vulnerable populations such as urban slums in tropical sub-saharan africa.201323705776
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