| the emergence of porcine circovirus 2b genotype (pcv-2b) in swine in canada. | since late 2004, the swine industry in the province of quebec has experienced a significant increase in death rate related to postweaning multisystemic wasting syndrome (pmws). to explain this phenomenon, 2 hypotheses were formulated: 1) the presence of a 2nd pathogen could be exacerbating the porcine circovirus 2 (pcv-2) infection, or 2) a new and more virulent pcv-2 strain could be infecting swine. in 2005, 13 pmws cases were submitted to the quebec provincial diagnostic laboratory and pcv-2 w ... | 2007 | 17824323 |
| phylogenetic networks to study the origin and evolution of porcine circovirus type 2 (pcv2) in cuba. | porcine circovirus type 2 (pcv2) is the essential etiological infectious agent of postweaning multisystemic wasting syndrome (pmws), which is considered one of the most economically important swine diseases worldwide. in this study, a comparison between methodologies based on classical phylogenetic trees and networks to infer the origin of pcv2 in cuba was performed. in addition, the mechanisms supporting the genetic variability of cuban pcv2 populations were investigated. a retrospective study, ... | 2011 | 21507587 |
| development and use of a multiplex real-time quantitative polymerase chain reaction assay for detection and differentiation of porcine circovirus-2 genotypes 2a and 2b in an epidemiological survey. | by the end of 2004, the canadian swine population had experienced a severe increase in the incidence of porcine circovirus-associated disease (pcvad), a problem that was associated with the emergence of a new porcine circovirus-2 genotype (pcv-2b), previously unrecovered in north america. thus, it became important to develop a diagnostic tool that could differentiate between the old and new circulating genotypes (pcv-2a and pcv-2b, respectively). consequently, a multiplex real-time quantitative ... | 2008 | 18776085 |
| comparative serologic and virologic study of commercial swine herds with and without postweaning multisystemic wasting syndrome. | a comparative serologic and virologic study was performed in pigs from 5 herds with postweaning multisystemic wasting syndrome (pmws) and 2 herds without pmws in quebec. in each herd, 60 blood samples were collected at 4-wk intervals from pigs from 3 to 23 wk of age. the serum was evaluated for the presence of antibodies to porcine circovirus type 2 (pcv2) and porcine reproductive and respiratory syndrome virus (prrsv), as well as for the presence of nucleic acid of pcv2, prrsv, an porcine parvo ... | 2003 | 12760476 |
| the emergence of a new strain of porcine circovirus-2 in ontario and quebec swine and its association with severe porcine circovirus associated disease--2004-2006. | in the late fall of 2004 more severe lesions of porcine circovirus-2 associated disease (pcvad) than usual occurred during an outbreak of porcine circovirus-2 (pcv-2) infection in ontario nursery and grower/finisher pigs. the lesions were of unprecedented severity and included diffuse bronchointerstitial pneumonia, granulomatous enteritis, vasculitis, interstitial nephritis, and new lesions of splenic infarction. some affected herds had up to 50% mortality. the outbreak correlated with the sudde ... | 2008 | 18505190 |