| characterization of clostridium difficile strains isolated from immunosuppressed inpatients in a hospital in rio de janeiro, brazil. | the aim of this work was to identify and characterize clostridium difficile strains from fecal and hospital environmental samples. c. difficile toxins were detected by elisa in 28.5% of the analyzed samples. four strains were isolated from immunosuppressed inpatients presenting antibiotic-associated diarrhea. all strains possessed tcda and tcdb genes and did not present neither the cdta and cdtb genes nor any significant deletions in the tcdc gene. pfge and pcr-ribotyping analysis showed that tw ... | 2009 | 19154793 |
| detection of cross-infection associated to a brazilian pcr-ribotype of clostridium difficile in a university hospital in rio de janeiro, brazil. | clostridium difficile is an important nosocomial enteric pathogen and is the etiological agent of pseudomembranous colites. recently, the rates of c. difficile infection (cdi) have increased worldwide, but in brazil few data about this situation and the incidence of clonal types of c. difficile exist. this study aimed to isolate and characterize c. difficile strains from samples obtained of a university hospital (hucff) in rio de janeiro city, brazil. cdi was identified by elisa in 27.1% of hucf ... | 2011 | 20623188 |
| an outbreak case of clostridium difficile-associated diarrhea among elderly inpatients of an intensive care unit of a tertiary hospital in rio de janeiro, brazil. | the aim of this study was to investigate clostridium difficile-associated diarrhea (cdad) in an intensive care unit (icu) of a tertiary hospital in rio de janeiro, brazil, and to characterize epidemiologically c. difficile strains obtained from an outbreak of cdad. within almost a 4-year surveillance period, cdad incidence was determined for the first time in brazil, and a 3-fold increase was observed in the average rate of cdad, featuring an outbreak. about 80% of the patients were over 65 year ... | 2010 | 20884155 |
| clostridium difficile infection among immunocompromised patients in rio de janeiro, brazil and detection of moxifloxacin resistance in a ribotype 014 strain. | clostridium difficile is a gram-positive spore forming anaerobic bacterium, often associated with nosocomial diarrhea and pseudomembranous colitis. the acquisition of this organism occurs primarily in hospitals through accidental ingestion of spores, and its establishment and proliferation in the colon results from the removal of members of the normal intestinal flora during or after antibiotic therapy. in this study, stool samples from patients admitted to the university hospital clementino fra ... | 2014 | 24907488 |
| incidence and importance of clostridium difficile in paediatric diarrhoea in brazil. | clostridium difficile strains were detected in 14 of 210 (6.7 %) faecal samples from children in rio de janeiro, brazil, by cultivating faeces on cycloserine/cefoxitin/fructose agar after alcohol-shock. two main groups of children were studied: inpatients (n = 96) and outpatients (n = 114). the inpatient group consisted of children on antibiotics or immunosuppressors who presented with diarrhoea and other children who did not present with diarrhoea and were not under an antibiotic or chemotherap ... | 2003 | 14614068 |
| [occurrence of clostridium difficile in the feces of children of rio de janeiro, rj, brazil]. | | 1988 | 3252437 |