Publications

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validation of syndromic algorithm for the management of genital ulcer diseases in china.1. to determine the aetiologies of genital ulcers in china. 2. to evaluate a modified who syndromic management algorithm for genital ulcer disease (gud).200212171666
macrolide resistance and molecular types of treponema pallidum causing primary syphilis in shanghai, china.the resurgence of syphilis in china requires laboratories to update their methods for molecular epidemiology investigation and surveillance. this study focuses on implementing polymerase chain reaction (pcr) diagnostic tests for syphilis and for detection of molecular subtypes and macrolide resistance among strains causing primary syphilis in the city of shanghai, china.200919583516
azithromycin treatment failure among primary and secondary syphilis patients in shanghai.azithromycin has been used to treat primary and secondary syphilis and as prophylaxis for sexual partners. we evaluated syphilis treatment failure in patients who received azithromycin therapy.201020644500
[analysis of hiv/syphilis/hcv infection among drug users in 15 cities, china].to study the hiv infection rate and relevant behavioural characteristics among drug users (dus) in the 15 cities of china-gates hiv/aids program.201021215121
molecular typing of treponema pallidum: a 5-year surveillance in shanghai, china.previously, a small study showed that 14f was the predominant subtype of treponema pallidum in shanghai, china. the result was quite different from the genotype distribution in other areas of china. this study aimed to identify the strain types of treponema pallidum in samples collected over a 5-year period in shanghai. from 2007 to 2011, genital swabs were collected from patients with syphilis from the shanghai skin disease hospital. positive specimens were typed by the enhanced typing method b ...201222972832
comparison of the cerebrospinal fluid (csf) toluidine red unheated serum test and the csf rapid plasma reagin test with the csf venereal disease research laboratory test for diagnosis of neurosyphilis among hiv-negative syphilis patients in china.in this study, we aimed to investigate the performance of nontreponemal antibody tests in cerebrospinal fluid (csf) specimens from syphilis patients. from september 2009 to september 2012, csf specimens were collected at the shanghai skin disease hospital in shanghai, china, from 1,132 syphilis patients without hiv infection, including 154 with symptomatic and 56 with asymptomatic neurosyphilis. all of the csf specimens underwent testing with a rapid plasma reagin (rpr) test, an rpr-v (commercia ...201424335955
high frequency of the 23s rrna a2058g mutation of treponema pallidum in shanghai is associated with a current strategy for the treatment of syphilis.the preferred drugs for the treatment of syphilis, benzathine and procaine penicillin, have not been available in shanghai for many years, and currently, the incidence of syphilis is increasing. alternative antibiotics for patients with syphilis during the benzathine and procaine penicillin shortage include macrolides. the failure of macrolide treatment in syphilis patients has been reported in shanghai, but the reason for this treatment failure remains unclear. we used polymerase chain reaction ...201526038763
prevalence of syphilis infection and associations with sexual risk behaviours among hiv-positive men who have sex with men in shanghai, china.the aims of this study were to understand the prevalence and correlates of syphilis infection among hiv-positive men who have sex with men (msm) in shanghai, china. a total of 200 hiv-positive msm participants were recruited using "snowball" sampling. participants were tested for syphilis and completed a one-time questionnaire which included demographic characteristics, sexual behaviours with male and female sexual partners, substance use, and use of antiretroviral medications. prevalence of syp ...201424285600
molecular epidemiological survey of treponema pallidum in pregnant women in the zhabei district of shanghai.objectives: to evaluate the epidemiological characteristics of syphilis, such as incidence, vertical transmission, and genotypes, in pregnant women in the zhabei district of shanghai. in addition, the changes in genotypes and the efficiency of genotyping was evaluated.201728126049
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