Publications

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primary human herpesvirus-6 and -7 infections, often coinciding, misdiagnosed as measles in children from a tropical region of brazil.we investigated primary human herpesvirus-6 and -7 (hhv-6, hhv-7) infections as a cause of rashes incorrectly diagnosed as measles in brazilian children. sera from 124 patients, aged 4 months to 17 years, from the states of rio de janeiro and espirito santo, in whom measles, rubella and parvovirus b19 infections had been excluded, were studied using indirect immunofluorescence antibody avidity tests; 38 (31%) had evidence of primary hhv-6 and/or hhv-7 infections. twenty four children had primary ...200314596528
role of human herpesvirus 6 infection in young brazilian children with rash illnesses.human herpesvirus type 6 (hhv-6) has been shown to infect almost all children by 4 years of age. primary infection causes an undifferentiated febrile illness, with approximately 30% of children exhibiting the classic clinical manifestations of exanthem subitum. even with typical clinical presentation, exanthem subitum is frequently misdiagnosed as measles or rubella. our aim was to describe the frequency and clinical manifestations of hhv-6 infection in children less than 4 years of age enrolled ...200818449066
the accuracy of anti-human herpesvirus 6 igm detection in children with recent primary infection.human herpesvirus 6 (hhv-6) has been shown to infect almost all children by 4 years of age. even with a typical clinical presentation, hhv-6 infection is misdiagnosed frequently as measles or rubella. the aim of this study was to assess the accuracy of the igm test for detection of recent primary hhv-6 infection. the study was conducted between january, 1998 and december, 2006 at primary health care units in niterói, rio de janeiro, brazil. sera from 185 children, in whom measles, rubella, dengu ...200818703091
detection of human herpesvirus 6 and 7 dna in saliva from healthy adults from rio de janeiro, brazil.in this study, we aimed to evaluate virus shedding in the saliva of healthy adults from the metropolitan region of the city of rio de janeiro, brazil, in order to verify the prevalence of both human herpesviruses 6 and 7 (hhv-6, hhv-7). the studied group comprised 182 healthy individuals at pedro ernesto university hospital, who were being seen for annual odontologic revisions. saliva specimens were subjected to a multiplex polymerase chain reaction (pcr) to detect the presence of hhv-6a, hhv-6b ...201021120365
detection of human herpesvirus 7 infection in young children presenting with exanthema subitum.in this study, we assessed the prevalence of human herpesvirus-7 (hhv-7) in 141 serum samples from children less than four years of age with exanthematic disease. all samples were negative for measles, rubella, dengue fever and parvovirus b19 infection. testing for the presence of human herpesvirus-6 (hhv-6)-specific high avidity igg antibodies by indirect immunofluorescence assay (ifa) revealed two main groups: one composed of 57 patients with recent primary hhv-6 infection and another group of ...201121655829
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