Publications

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validity of the vaginal discharge algorithm among pregnant and non-pregnant women in nairobi, kenya.to evaluate the validity of different algorithms for the diagnosis of gonococcal and chlamydial infections among pregnant and non-pregnant women consulting health services for vaginal discharge in nairobi, kenya.200010817066
a randomized, placebo-controlled trial of monthly azithromycin prophylaxis to prevent sexually transmitted infections and hiv-1 in kenyan sex workers: study design and baseline findings.our objectives were to describe the baseline findings of a trial of antibiotic prophylaxis to prevent sexually transmitted infections (stis) and hiv-1 in a cohort of nairobi female sex workers (fsws). a questionnaire was administered and a medical examination was performed. hiv-negative women were randomly assigned to either one gram azithromycin or placebo monthly. mean age of the 318 women was 32 years, mean duration of sex work 7 years and mean number of clients was 4 per day. high-risk behav ...200011138916
clinical characteristics associated with mycoplasma genitalium among female sex workers in nairobi, kenya.the prevalence of mycoplasma genitalium is high in vulnerable populations of women in low-resource settings. however, the epidemiology of infection in these populations is not well established. to determine the prevalence of mycoplasma genitalium and its association with cervical cytology and other correlates, we recruited 350 female sex workers (fsw) who were 18 to 50 years old in nairobi, kenya, for a cross-sectional study. a questionnaire was administered at baseline to obtain information on ...201425100823
the role of chlamydia trachomatis in high-risk human papillomavirus persistence among female sex workers in nairobi, kenya.little is known about risk factors for persistent high-risk human papillomavirus (hrhpv) infection in low-income settings, and prior research has not quantified the relative duration of hrhpv infections stratified by risk factors. we compared the duration of hrhpv infection among female sex workers (fsws) by exposure to sexually transmitted infections (stis), using a highly sensitive biomarker assay.201525970306
microbiology of vaginal discharge in nairobi, kenya.among women attending a sexually transmitted disease (std) clinic in nairobi with vaginal discharge, neisseria gonorrhoeae and chlamydia trachomatis were isolated from the cervix in 32 (26%) of 122 and four (7%) of 58 women respectively. infection with trichomonas vaginalis, candida albicans, gardnerella vaginalis, and mycoplasma spp were diagnosed in 42 of 122 (34%), 26 of 110 (24%), 75 of 100 (75%), and 42 of 89 (47%) women respectively. mixed infections with at least two pathogens were found ...19836405973
monthly antibiotic chemoprophylaxis and incidence of sexually transmitted infections and hiv-1 infection in kenyan sex workers: a randomized controlled trial.sexually transmitted infections (stis) are common in female sex workers (fsws) and may enhance susceptibility to infection with human immunodeficiency virus type 1 (hiv-1).200415173146
prevalence and risk factors of three curable sexually transmitted infections among women in nairobi, kenya.sexually transmitted infections (stis) are a major public health problem, especially in developing countries. the complications of untreated stis in the female genital tract and their role in adverse pregnancy and perinatal outcomes have been well documented. the prevalence of stis in kenya among women in the general population has not been extensively studied and there is a lack of guidelines for screening of non-pregnant women. knowledge of the prevalence of curable stis among this population ...201627026347
high-risk human papillomavirus messenger rna testing in physician- and self-collected specimens for cervical lesion detection in high-risk women, kenya.little is known about the performance of physician-versus self-collected specimens for high-risk human papillomavirus (hrhpv) messenger rna (mrna) testing or risk factors for hrhpv mrna positivity in physician- versus self-collected specimens. we compared the performance of hrhpv mrna testing of physician- and self-collected specimens for detecting cytological high-grade squamous intraepithelial lesions or more severe (≥hsil) and examined risk factors for hrhpv mrna positivity in female sex work ...201323965776
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