Publications

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habitats of the sandfly vectors of leishmania tropica and l. major in a mixed focus of cutaneous leishmaniasis in southeast tunisia.from 2009 to 2010, 3129 sandflies were caught in cdc light traps placed in various habitats in ghomrassen, tataouine governorate, southeast tunisia, a mixed focus of human cutaneous leishmaniasis caused by leishmania tropica and leishmania major. species diversity was quantified in anthropogenic, semi-anthropogenic and semi-natural locations. sandflies were identified according to morphological characters and also by the comparative sequence analysis of a fragment of the mitochondrial cytochrome ...201121605538
epidemiologic and clinical features of cutaneous leishmaniasis in southeastern tunisia.species-specific diagnosis was performed in 66 patients with cutaneous leishmaniasis (cl) living in tataouine focus in southeastern tunisia. leishmania dna was extracted directly from dermal scrapings (n = 66) and from parasites obtained in culture (n = 12). species were identified by using polymerase chain reaction-restriction fragment length polymorphism analysis for internal transcribed spacer region 1 and isoenzyme analysis. leishmania tropica and l. major were identified in 31 (47%) and 35 ...201021036833
[epidemiology of leishmania (l.) infantum, l. major and l. killicki in tunisia: results and analysis of the identification of 226 human and canine isolates].the epidemiological situation of leishmaniasis in tunisia is characterised by the co-existence in a very limited territory (165,000 km2, sahara included), of 4 clinical forms: the infantile visceral leishmaniasis (vl) and 3 cutaneous leishmaniasis (cl) forms (sporadic, zoonotic and chronic). in addition to the useful epidemiological data, identification of the causative parasitic species is essential to determine the geographic distribution of each form and to select appropriate therapeutic proc ...200818956815
cutaneous leishmaniasis in tunisia: results of the iso-enzymatic characterization of 71 strains.three clinico-epidemiological forms of cutaneous leishmaniasis (cl) exist in tunisia: zoonotic cutaneous leishmaniasis (zcl; epidemic in the centre and the south-west); sporadic cutaneous leishmaniasis (scl; found in the north); and chronic cutaneous leishmaniasis (ccl; originally described from tataouine, in the south-east). as few isolates of leishmania from tunisian cases of cl have been typed, isolates were collected, using nnn medium, from 71 such cases. most (59) of the cases investigated ...200515701250
leishmaniasis in central and southern tunisia: current geographical distribution of zymodemes.the authors report the identification of leishmania strains isolated from the centre and the south of tunisia. 266 strains were isolated between 1998 and 2006 from human (n=221 strains) and dogs (n=45 strains) hosts. the isoenzymatic identification exhibits the presence of in total five zymodemes belonging to three leishmanio complexes: leishmania infantum, l. major and l. killicki. all strains isolated from human and canine visceral leishmaniasis belonged to l. infantum. zymodeme mon-1 was the ...200717933302
first report on natural infection of phlebotomus sergenti with leishmania tropica in a classical focus of leishmania major in tunisia.in tunisia, chronic cutaneous leishmaniasis due to leishmania tropica is an important health problem. its spreading has not been fully elucidated. information on sandfly vectors, as well as their associated leishmania species, is of paramount importance since vector dispersion is one of the major factors responsible for pathogen dissemination. ninety-seven unfed females belonging to the genera sergentomyia and phlebotomus were collected between june and august 2015 using sticky paper traps. poly ...201728719307
[investigation and analysis of an outbreak of cutaneous leishmaniasis in ksar ouled dabbab, tataouine (tunisia), 2012-2013].zoonotic cutaneous leishmaniasis (zcl), due to leishmania major, and chronic cl, due to l. tropica, are endemic in the governorate (administrative subdivision) of tataouine (southeast tunisia). this study aims to analyze epidemiologic, clinical, parasitologic, and entomologic data collected during the 2012-2013 epidemic in ksar ouled dabbab (kod).201526039183
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