| first microscopical and molecular-based characterization of leishmania major within naturally infected phlebotomus salehi (diptera; psychodidae) in fars province, southern iran. | zoonotoc cutaneous leishmaniasis is endemic in several parts of iran. jahrom district is one of the most important endemic foci of leishmaniasis located in fars province, southern iran. to identify the vectors of leishmaniasis in this area, a total of 349 sandflies were collected during may to august 2009. they were caught from outdoors in five regions of jahrom district including villages of mousavieh, ghotb-abad, heydar-abad, fath-abad and jahrom county. eleven species of phlebotomine (three ... | 2011 | 22185942 |
| first detection of leishmania major in rattus norvegicus from fars province, southern iran. | zoonotic cutaneous leishmaniasis is an important health problem in iran and a great economic burden on the health resources. in southern iran (fars province), meriones libycus was reported as the main reservoir of zoonotic cutaneous leishmaniasis in arsanjan and marvdasht cities, and tatera indica and gerbillus spp. were the reservoirs reported in larestan and kharameh districts. because of an increase in human cutaneous leishmaniasis in fars province, this study was performed to identify the ro ... | 2010 | 20426685 |
| vectors and reservoirs of cutaneous leishmaniasis in marvdasht district, southern islamic republic of iran. | an epidemiological study was made of vectors and reservoirs of cutaneous leishmaniasis in rural regions of marvdasht, fars province, southern islamic republic of iran during 2003-04. using live traps, 126 rodents were collected: 75.4% were meriones libycus, 14.3% cricetulus migratorius and 10.3% microtus arvalis. eight out of 95 meriones libycus (8.4%) were found to be infected with leishmania major, identified by nested-pcr; none of the other rodents were positive. female sandflies were collect ... | 2007 | 17687843 |
| a search for the rodent hosts of leishmania major in the larestan region of southern iran: demonstration of the parasite in tatera indica and gerbillus sp., by microscopy, culture and pcr. | zoonotic cutaneous leishmaniasis (cl) caused by leishmania major occurs widely in iran, where several species of rodent serve as the parasite's 'reservoir' hosts. in an attempt to identify the rodent hosts in the larestan region, which lies in the fars province of southern iran (where the incidence of human cl has been rising), 32 rodents (20 tatera indica, eight meriones crassus, four gerbillus sp.) were caught and checked for leishmanial infection. using two detection methods (the microscopica ... | 2007 | 17524246 |
| meriones libycus is the main reservoir of zoonotic cutaneous leishmaniasis in south islamic republic of iran. | a study was made in rural regions around neiriz city, fars province in the south of the islamic republic of iran during 2002-03 to further investigate a new focus of zoonotic cutaneous leishmaniasis. meriones libycus was the dominant rodent (100% of 65 rodents collected) and 4.6% were naturally infected with the amastigote form of leishmania spp. promasigotes were identified as l. major. this confirms m. libycus as the main reservoir host of zoonotic cutaneous leishmaniasis in southern parts of ... | 2006 | 17037718 |
| low diversity of leishmania parasites in sandflies and the absence of the great gerbil in foci of zoonotic cutaneous leishmaniasis in fars province, southern iran. | fars province lies to the south of the main foci of zoonotic cutaneous leishmaniasis (zcl) caused by leishmania major in central and northern iran, and its zcl foci might have emerged more recently because of different transmission cycles. however, there have been limited studies of the parasites infecting the regional sandfly vectors. | 2013 | 23604865 |
| first molecular detection of leishmania major within naturally infected phlebotomus salehi from a zoonotic cutaneous leishmaniasis focus in southern iran. | human cutaneous leishmaniasis (cl) is a major notifiable public health problem in many parts of iran. it is often caused by the zooflagellate parasite leishmania major which is mainly transmitted by the bites of female phlebotomine sandflies belonging to the genus phlebotomus (diptera: psychodidae). the annual incidence of cl in fars province, southern iran, was about 108-144 in 2007. the leishmanial infections of wild sandflies that may act as vectors were thus investigated at an endemic focus ... | 2012 | 22543597 |
| post-earthquake outbreak of cutaneous leishmaniasis in a rural region of southern iran. | human cutaneous leishmaniasis (cl) is of increasing public-health importance in iran. on 10 july 2003, two mild earthquakes struck the rural town of zarindasht in the southern iranian province of fars. the results of passive detection of cl cases in this town (in which patients with any skin lesions were evaluated) from april 2002 to april 2004 indicated that the earthquakes may have led to an outbreak of the disease; annual incidence increased from 58·6 detected cases/100,000 in the 12 months b ... | 2011 | 21801500 |
| first detection of leishmania infantum dna in wild caught phlebotomus papatasi in endemic focus of cutaneous leishmaniasis, south of iran. | to identify the vectors and reservoirs of cutaneous leishmaniasis in the endemic focus of farashband, fars province, south of iran. | 2013 | 24075350 |
| the changing profile of cutaneous leishmaniasis in a focus of the disease in jahrom district, southern iran. | human cutaneous leishmaniasis (cl) is endemic in several parts of iran, and there is an urban focus of the disease in the district of jahrom, which forms part of the southern province of fars. to explore the current profile of the disease in jahrom district, samples were taken from the skin lesions of 40 cases of cl patients in the district, so that the causative parasites could be identified, to species, in a nested pcr. although leishmania tropica has been identified, in the past, as the cause ... | 2010 | 20819305 |
| first report on isolation of leishmania tropica from sandflies of a classical urban cutaneous leishmaniasis focus in southern iran. | shiraz district in south of iran is a classical focus of cutaneous leishmaniasis (cl) and previous research has consistently documented the etiologic agent to be leishmania tropica and leishmania major in urban and rural areas, respectively. however, none of the phlebotomus sergenti, a known vector for l. tropica, of the region has been found infected. we report the first isolation of l. tropica from sandflies in urban community of southern part of shiraz city. parasite polymerase chain reaction ... | 2010 | 20570590 |
| a new focus of zoonotic cutaneous leishmaniasis in shiraz, iran. | cutaneous leishmaniasis (cl) continues to be an increasing public health problem in iran. shiraz, a city in fars province in southwestern iran, is one of the endemic foci of cl. however, there is no formal report of endemicity of cl in rural areas of shiraz. to our knowledge, this is the first report of an epidemic of zoonotic cl in this area. the purpose of this study was to examine the epidemiological features of leishmaniasis in three villages in rural areas of shiraz and to identify the caus ... | 2009 | 19223055 |
| first detection of leishmania infantum in phlebotomus (larroussius) major (diptera: psychodidae) from iran. | ghir-karzin district is one of the most important endemic foci of visceral leishmaniaisis (vl) in fars province of southern iran. to identify the vector(s) of leishmania in this focus, a total of 2,539 sand flies were collected during june to september 2005. eleven species (six phlebotomus and five sergentomyia) were identified, of which phlebotomus papatasi scopoli and phlebotomus major annandale were the first (37.4%) and third (11.2%) most common species, respectively. natural leptomonad infe ... | 2008 | 18714874 |
| the pcr-based detection of leishmania major infections in meriones libycus (rodentia: muridae) from southern iran. | cutaneous leishmaniasis (cl) is an increasing public-health problem in the countries of the mediterranean region. in southern iran, for example, the incidence of cl has more than doubled over the last decade. as part of an investigation of this worrying trend, the leishmanial infections of the wild rodents that may act as reservoir hosts were investigated in the iranian province of fars. overall, 82 rodents, 56 of them libyan jirds (meriones libycus), were collected, in live traps, from a new, h ... | 2003 | 14754493 |
| characterization of leishmania isolated in iran: 1. serotyping with species specific monoclonal antibodies. | a total of 156 isolates of leishmania from patients with cutaneous leishmaniasis and one isolate from gerbil were characterized using standard monoclonal antibodies (mab) in elisa and ifa test systems. the geographic distribution of the isolates was 30 isolates in shiraz, 28 in kerman and 98 in tehran. a total of 63, 72, and three leishmania promastigote isolates preferentially reacted with anti-leishmania tropica mab (a11), anti-leishmania major mab (t1) and anti-leishmania infantum mab (d2), r ... | 2000 | 10838213 |
| molecular characterization of leishmania spp. in reservoir hosts in endemic foci of zoonotic cutaneous leishmaniasis in iran. | zoonotic cutaneous leishmaniasis (zcl) is an expanding disease and a public health issue in iran. in the present study, rate of natural infection of rodent populations with leishmania was investigated in six endemic foci including 28 villages in golestan, esfahan, yazd, fars, khuzestan and ilam provinces. a total of 593 rodents were captured and identified as rhombomys opimus (n = 325), meriones libycus (n = 171), meriones persicus (n = 27), tatera indica (n = 37), nesokia indica (n = 12), rattu ... | 2013 | 23951928 |
| diversity of leishmania species and of strains of leishmania major isolated from desert rodents in different foci of cutaneous leishmaniasis in iran. | zoonotic cutaneous leishmaniasis (zcl) is a polymorphic disease which may show various symptoms. genetic diversity of the parasite is suggested to be one of the factors influencing the clinical manifestation of the disease. | 2014 | 24980555 |
| molecular detection of leishmania parasites and host blood meal identification in wild sand flies from a new endemic rural region, south of iran. | zoonotic cutaneous leishmaniosis (zcl) remains the most crucial vector-borne public health disease particularly in endemic rural parts of iran. the main aim of this study is to identify wild sand flies (diptera: psychodidae), determine their infection rate, and differentiate their host blood meal sources using the polymerase chain reaction-restriction fragment length polymorphism (pcr-rflp) technique. sand fly populations were caught with sticky paper traps from 10 different villages in the coun ... | 2017 | 27854189 |