| cutaneous manifestations of human immunodeficiency virus in lusaka, zambia. | of the 1124 human immunodeficiency virus (hiv)-infected patients studied, one or more cutaneous lesions were found in 113 (98.3%) of the 115 patients with acquired immunodeficiency syndrome (aids) and in 541 (53.6%) of 1009 patients with aids-related complex (arc). kaposi's sarcoma, multidermatomal, necrotic herpes zoster, and pruritic maculopapular rashes are common cutaneous manifestations of aids and its related complex (arc) in zambia. the maculopapular rash results from a lymphoplasmacytic ... | 1988 | 2971691 |
| childhood cancers in zambia before and after the hiv epidemic. | human immunodeficiency virus (hiv) related cancers in children are not as common and as well described as in adults. an hiv epidemic has been prevalent in zambia since 1983-1984. to study the effect of the epidemic on the epidemiology of cancers in children a retrospective study was undertaken at the university teaching hospital (uth), lusaka, zambia. all the histopathological records from 1980 to 1992 were reviewed and all cases of cancers in children less than 14 years of age were analysed. in ... | 1995 | 7574850 |
| pattern of adult malignancies in zambia (1980-1989) in light of the human immunodeficiency virus type 1 epidemic. | this study analysed histopathological and haematology records of 7836 neoplasms seen during the period 1980-1989 at the university teaching hospital, lusaka, zambia. the crude incidence rate of each malignancy per 100,000 adults per year was calculated and the patterns of malignancies were compared for the periods 1980-1983 and 1984-1989, the later coinciding with the advent of the human immunodeficiency virus (hiv) epidemic. the six most common tumours were carcinoma of the cervix (19.6%), kapo ... | 1995 | 7636927 |
| influence of hiv epidemic on the incidence of kaposi's sarcoma in zambian children. | acquired immunodeficiency syndrome-associated kaposi's sarcoma (ks) is well documented in adults. however, very little information is available about ks in the pediatric age group. a retrospectively study was undertaken at the university teaching hospital (uth), lusaka, zambia, to define the incidence and clinical profile of ks in zambian children over the last 13 years and to determine the influence, if any, of the current human immunodeficiency virus (hiv) epidemic on the pattern of pediatric ... | 1995 | 8548353 |
| postnatal human herpesvirus 8 and human immunodeficiency virus type 1 infection in mothers and infants from zambia. | the specific route and timing of human herpesvirus (hhv) 8 infection in regions where kaposi sarcoma is endemic are not known. hhv-8 infection and any risk factors that may be associated with hhv-8, including human immunodeficiency virus (hiv) type 1 infection, were monitored during the 12-month postdelivery period for 416 mothers and 485 infants from lusaka, zambia. hhv-8 incident infection rates during this period were 3.2 and 5.3 infections/100 person-years for infants and mothers, respective ... | 2003 | 12599072 |
| epidemiological characteristics of human herpesvirus-8 infection in a large population of antenatal women in zambia. | comprehensive data describing epidemiological characteristics of the human herpesvirus-8 or kaposi's sarcoma-associated herpesvirus (hhv-8 or kshv) infection among pregnant women in a central sub-saharan africa are not available. this study determined virus prevalence estimates and the risk factors associated with hhv-8 infection. cross-sectional, enrollment visit data were analyzed from a prospective cohort study of perinatal transmission of hhv-8 in lusaka, zambia. exposure data were obtained ... | 2005 | 15543582 |
| the zambia children's ks-hhv8 study: rationale, study design, and study methods. | the epidemic of human immunodeficiency virus in zambia has led to a dramatic rise in the incidence of human herpesvirus-8 (hhv-8)-associated kaposi's sarcoma in both adults and children. however, there is a paucity of knowledge about the routes of hhv-8 transmission to young children. the zambia children's ks-hhv8 study, a large, prospective cohort study in lusaka, zambia, was launched in 2004 to investigate the role of household members as a source of hhv-8 infection in young children and socia ... | 2011 | 21447476 |
| increasing kaposi's sarcoma-associated herpesvirus seroprevalence with age in a highly kaposi's sarcoma endemic region, zambia in 1985. | kaposi's sarcoma (ks)-associated herpesvirus (kshv) is a newly discovered virus found in all forms of ks. in the united states, kshv infection appears to be most common amongst individuals at high-risk for ks. preliminary data from africa suggest that kshv infection may be much more common in the general population. | 1998 | 9792393 |
| surgery, surgical pathology and hiv infection: lessons learned in zambia. | hiv (human immunodeficiency virus) infection is prevalent in many areas of sub-saharan africa. seropositivity rates reach 10-15% in urban adults, 21% in critically ill adults and 30% in surgical inpatients aged 21-40 years. aids (acquired immune deficiency syndrome) is a multisystem disease which presents to the surgeon with a wide range of pathologies including kaposi's sarcoma, lymphadenopathy and sepsis. the more common sites for sepsis are the female genital tract, anorectum, pleural cavity, ... | 1994 | 7863725 |
| clinical and epidemiological features of hiv infection at a referral clinic in zambia. | among 1,350 patients with serologically confirmed hiv-1 infection evaluated at the dermatovenerealogy clinic, university teaching hospital. lusaka, through march 1987, 125 (9.3%) had aids, 1,178 (87.3%) had aids-related complex, and 46 (3.5%) were asymptomatic. the male to female ratio of cases was 1.5:1 and women were younger (mean age of 26.2 years) than were men (mean age of 31.2 years). hiv-infected persons had significantly more lifetime sex partners than uninfected persons; other risk fact ... | 1990 | 2293647 |
| early childhood infection by human herpesvirus 8 in zambia and the role of human immunodeficiency virus type 1 coinfection in a highly endemic area. | kaposi's sarcoma occurs at high incidence among zambian adults and children, but there is a paucity of data on human herpesvirus 8 (hhv-8) incidence and routes of infection, especially in children. between 1998 and 2004, the authors conducted a prospective study of viral transmission in a cohort of 684 children in lusaka, zambia, to estimate the annual incidence of hhv-8 from birth through 48 months of age. maternal and pediatric human immunodeficiency virus type 1 (hiv-1) infection status was a ... | 2008 | 18515794 |