dreamtime, devastation and deviation: australia's contribution to the chemotherapy of human parasitic infections. | there are three areas in which australian scientists have made outstanding contributions to the study of the chemotherapy of human parasitic infections. naturally occurring products of plants have great potential as antiparasitic agents and although several native species have been shown to have antimalarial and anthelmintic activity, their potential as chemotherapeutic agents has not been fully realised; secondly, the demands of war ensured that the army malaria unit at cairns carried out metic ... | 1995 | 8847165 |
real-time pcr detection of pathogenic microorganisms in roof-harvested rainwater in southeast queensland, australia. | in this study, the microbiological quality of roof-harvested rainwater was assessed by monitoring the concentrations of escherichia coli, enterococci, clostridium perfringens, and bacteroides spp. in rainwater obtained from tanks in southeast queensland, australia. samples were also tested using real-time pcr (with sybr green i dye) for the presence of potential pathogenic microorganisms. of the 27 rainwater samples tested, 17 (63%), 21 (78%), 13 (48%), and 24 (89%) were positive for e. coli, en ... | 2008 | 18621865 |
implications of faecal indicator bacteria for the microbiological assessment of roof-harvested rainwater quality in southeast queensland, australia. | the study aimed to evaluate the suitability of escherichia coli, enterococci, and clostridium perfringens for assessing the microbiological quality of roof-harvested rainwater and assessing whether the concentrations of these faecal indicators can be used to predict the presence or absence of specific zoonotic bacterial or protozoan pathogens. from a total of 100 samples tested, 58%, 83%, and 46% of samples were found to be positive for, respectively, e. coli, enterococci, and clostridium perfri ... | 2010 | 20657617 |
fecal indicators and zoonotic pathogens in household drinking water taps fed from rainwater tanks in southeast queensland, australia. | in this study, the microbiological quality of household tap water samples fed from rainwater tanks was assessed by monitoring the numbers of escherichia coli bacteria and enterococci from 24 households in southeast queensland (seq), australia. quantitative pcr (qpcr) was also used for the quantitative detection of zoonotic pathogens in water samples from rainwater tanks and connected household taps. the numbers of zoonotic pathogens were also estimated in fecal samples from possums and various s ... | 2012 | 22020514 |
giardiasis in mount isa, north-west queensland. | a random survey of 680 dwellings was undertaken to determine the prevalence and mode of transmission of giardia intestinalis in mount isa. of the population, 4.5% were shown to have cysts in their stools; the highest prevalence rate of 12.0% occurred in children aged one to five years. epidemiological studies strongly suggest that the disease, which is endemic in the city, is being transmitted by hand-to-mouth contamination; schools, preschools, kindergartens and play groups are important foci o ... | 1986 | 3713567 |
health risk from the use of roof-harvested rainwater in southeast queensland, australia, as potable or nonpotable water, determined using quantitative microbial risk assessment. | a total of 214 rainwater samples from 82 tanks were collected in urban southeast queensland (seq) in australia and analyzed for the presence and numbers of zoonotic bacterial and protozoal pathogens using binary pcr and quantitative pcr (qpcr). quantitative microbial risk assessment (qmra) analysis was used to quantify the risk of infection associated with the exposure to potential pathogens from roof-harvested rainwater used as potable or nonpotable water. of the 214 samples tested, 10.7%, 9.8% ... | 2010 | 20851954 |
molecular typing of giardia duodenalis in humans in queensland - first report of assemblage e. | little is known about the genetic diversity of the protozoan parasite, giardia duodenalis, infecting humans in queensland, australia. the present study typed 88 microscopically giardia-positive isolates using assemblage-specific primers at the triose phosphate isomerase (tpi) gene and sequenced a subset of isolates at the glutamate dehydrogenase (gdh) gene (n = 30) and tpi locus (n = 27). using the tpi-assemblage specific primers, g. duodenalis assemblage a and assemblage b were detected in 50% ... | 2017 | 28482937 |
human and bovine adenoviruses for the detection of source-specific fecal pollution in coastal waters in australia. | in this study, the host-specificity and -sensitivity of human- and bovine-specific adenoviruses (hs-avs and bs-avs) were evaluated by testing wastewater/fecal samples from various animal species in southeast, queensland, australia. the overall specificity and sensitivity of the hs-avs marker were 1.0 and 0.78, respectively. these figures for the bs-avs were 1.0 and 0.73, respectively. twenty environmental water samples were collected during wet conditions and 20 samples were colleted during dry ... | 2010 | 20891037 |
two distinct varieties of giardia in a mixed infection from a single human patient. | twenty-five in vitro cultures of giardia duodenalis derived from a brisbane patient were established to assess the genetic heterogeneity of a population. each of the established lines carried a predominance of one of two distinct varieties of giardia. the two varieties were heterogeneous by four unambiguous criteria that were representative of the whole genome. these included restriction enzyme polymorphisms, hybridization with the cloned rdna repeat and with a gene encoding a cysteine-rich surf ... | 1994 | 7914131 |