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[analysis on the epidemiological and genetic characteristics of enterovirus type 71 and coxsackie a16 virus infection in jiangsu, china].to determine the epidemiological features of hand-foot-and-mouth disease (hfmd) outbreaks and the genetic characteristics of enterovirus type 71(ev71) isolates from patients in lianyungang, jiangsu province in may, 2008.200919731523
[association between hand-foot-and-mouth disease in xi'an and enterovirus 71].to isolate the prevalent strain of enterovirus 71 (ev71) in xi'an area in 2008, and compare the concordance of viral isolation, reverse transcription polymerase chain reaction (rt-pcr) and immunofluorescent technique in detecting ev71, find the fast and effective method for detection, and analyze the differences between the ev71 strains isolated from xi'an and fuyang, anhui.200919951516
an emerging recombinant human enterovirus 71 responsible for the 2008 outbreak of hand foot and mouth disease in fuyang city of china.hand, foot and mouth disease (hfmd), a common contagious disease that usually affects children, is normally mild but can have life-threatening manifestations. it can be caused by enteroviruses, particularly coxsackieviruses and human enterovirus 71 (hev71) with highly variable clinical manifestations. in the spring of 2008, a large, unprecedented hfmd outbreak in fuyang city of anhui province in the central part of southeastern china resulted in a high aggregation of fatal cases. in this study, ...201020459851
epidemiology of hand, foot, and mouth disease and genotype characterization of enterovirus 71 in jiangsu, china.in the spring of 2008, an ev71-caused hand, foot, and mouth disease (hfmd) outbreak occurred in fuyang city, anhui province, china. jiangsu province that borders auhui to the east is presumed as a key station for the spread of ev71 to other regions of the yangtze river delta.201020719557
a comparison of the biological characteristics of ev71 c4 subtypes from different epidemic strains.the comparative analysis of the biological characterization and the genetic background study of ev71 circulating strains is commonly recognized as basic work necessary for development of an effective ev71 vaccine. in this study, we sequenced five ev71 circulating strains, isolated from fuyang, hefei, kunming and shenzhen city of china and named them fy-23, fy-22, h44, k9 and s1 respectively. the sequence alignment demonstrated their genotypes be c4. the genetic distance of the vp1 gene from thes ...201020960306
retrospective seroepidemiology indicated that human enterovirus 71 and coxsackievirus a16 circulated wildly in central and southern china before large-scale outbreaks from 2008.large nationwide outbreaks of hand, foot, and mouth disease (hfmd) occurred in china from 2008; most of the cases were in children under 5 years. this study aims to identify the situation of natural human enterovirus 71 (hev71) and coxsackievirus a16 (cva16) infections in children before 2008 in china.201021050463
[the genetical evolution of the full length genes of 5 ev 71 strains from 5 shenzhen patients with hand-food-mouth disease associated with ev71 infection].to investigate the characteristics of molecular epidemiology and molecular evolution of 5 ev 71 (enterovirus 71, ev71) strains from 5 shenzhen patients with hand-food-mouth disease associated with ev 71 infection.201121789856
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