| [study on the characteristics and risk factors for hand-foot-mouth disease in guangdong province]. | | 2009 | 19799158 |
| [seroepidemical study of coxsackievirus a 16, in four provinces, china, 2005]. | to study the situation of 1- 5-years-old children's antibody against coxsackievirus a group 16 strain (cva16) in guangdong, heilongjiang,yunnan province and xinjiang uygur autonomous regions, china, 2005, it can offer scientific evidences for preventing and controlling cva16 causative hand-food and mouth disease. | 2009 | 20104748 |
| [etiology of hand, foot and mouth disease in guangzhou in 2008]. | to understand the etiology of hand, foot and mouth disease (hfmd) in guangzhou area in 2008. | 2010 | 20426938 |
| a comparison of the biological characteristics of ev71 c4 subtypes from different epidemic strains. | the comparative analysis of the biological characterization and the genetic background study of ev71 circulating strains is commonly recognized as basic work necessary for development of an effective ev71 vaccine. in this study, we sequenced five ev71 circulating strains, isolated from fuyang, hefei, kunming and shenzhen city of china and named them fy-23, fy-22, h44, k9 and s1 respectively. the sequence alignment demonstrated their genotypes be c4. the genetic distance of the vp1 gene from thes ... | 2010 | 20960306 |
| retrospective seroepidemiology indicated that human enterovirus 71 and coxsackievirus a16 circulated wildly in central and southern china before large-scale outbreaks from 2008. | large nationwide outbreaks of hand, foot, and mouth disease (hfmd) occurred in china from 2008; most of the cases were in children under 5 years. this study aims to identify the situation of natural human enterovirus 71 (hev71) and coxsackievirus a16 (cva16) infections in children before 2008 in china. | 2010 | 21050463 |
| an enterovirus 71 epidemic in guangdong province of china, 2008: epidemiological, clinical, and virogenic manifestations. | enterovirus 71 (ev71) is shown to be a major causative agent in outbreaks of hand, foot, and mouth disease (hfmd) reported in guangdong (gd) province of china in 2008. a total of 48,876 hfmd cases (131 severe and 21 fatal) were reported to the gd hfmd web-based surveillance system, which covers 871 clinics. the main causes of death included central nervous system damage, heart failure, and pulmonary edema. the incidence rate was 52 per 100,000, and the epidemic peak appeared in may and june. ev7 ... | 2011 | 21266750 |
| a large outbreak of hand, foot, and mouth disease caused by ev71 and cav16 in guangdong, china, 2009. | a large outbreak of hand, foot and mouth disease (hfmd) occurred in guangdong, china, in 2009. a total of 92,749 cases were officially reported to the center for disease control and prevention of guangdong (gdcdc). to clarify the pathogen causing the outbreak, 600 specimens, including stool, rectal swabs, vesicular swabs, cerebrospinal fluid, and throat swabs, were collected from 541 patients and subjected to one-step rt-pcr. four hundred eighty-nine of 541 patient samples were positive for ente ... | 2011 | 21305327 |
| seroepidemiology of human enterovirus71 and coxsackievirusa16 among children in guangdong province, china. | hand, foot and mouth disease (hfmd) is a common pediatric illness. mainly induced by the enterovirus 71 and coxsackievirus a 16 infections, the frequently occurred hfmd outbreaks have become a serious public health problem in southeast asia. currently,only a few studies have investigated the human immunity to hfmd in china. in this study, we conducted a cohort study in guangdong province, china. | 2013 | 23855481 |
| [an analysis of the characteristics and etiology of hand, foot and mouth disease in a guangzhou sentinel hospital from may to december, 2008]. | to analyze the characteristics and etiology of hand, foot and mouth disease (hfmd) in a sentinel hospital of guangzhou. | 2010 | 20584671 |
| emergence of enterovirus 71 "double-recombinant" strains belonging to a novel genotype d originating from southern china: first evidence for combination of intratypic and intertypic recombination events in ev71. | hand-foot-mouth disease due to enterovirus 71 (ev71) and coxsackievirus a16 (ca16) has recently caused large outbreaks in mainland china in 2008. we performed complete genome sequencing on two ev71 (sz/hk08-5 and sz/hk08-6) and two ca16 (sz/hk08-3 and sz/hk08-7) strains from patients in shenzhen, china. phylogenetic, similarity plot and bootscan analyses revealed recombination between ev71 genotypes b and c at the 2a-2b junction, and between ev71 genotype b and ca16 strain g-10 in the 3c region ... | 2010 | 20549263 |
| [genetype characteristics of enterovirus type 71 in shenzhen from 2005 to 2008]. | genetic characteristics of enterovirus type 71 in shenzhen from 2005 to 2008 were analyzed. all samples were detected by rt-pcr using ev71-specific primers. the vp1s of ev71 strains were amplified and sequenced. a phylogenetic tree was constructed by comparison of the sequences with those of subgenotype a, b and c using dnastar, bioedit and mega 3.1 softwares. the vp1 nucleotide sequences of 17 strains of shenzhen shared 95.3%-99.4% identities with cluster c4a, and one strain shared 93.0%-95.6% ... | 2009 | 20077930 |
| [the epidemiologic and virological analysis of an outbreak of hand, foot, and mouth disease in inner mongolia in 2007]. | in 2007, an outbreak of hand, foot, and mouth disease (hfmd) occurred in jungar banner, erdos city, inner mongolia autonomous region, china fever, vesicular exanthema on the hands, feet, mouth, and buttocks were presented in most of the patients. most of the patients were infants less than 5 years old, and an obvious peak period appeared in the disease outbreak. from 28 hospitalized patients, 23 stool specimens and 6 throat swab specimens were collected for enterovirus isolation, and 15 enterovi ... | 2009 | 19634756 |
| [genotype analysis of enterovirus type 71 detected from patients with hand-foot-mouth disease in shenzhen]. | to carry out genotype analysis of enterovirus type 71, detected from hand-foot-mouth disease patients in shenzhen in 2004. | 2008 | 19103116 |
| [the genetical evolution of the full length genes of 5 ev 71 strains from 5 shenzhen patients with hand-food-mouth disease associated with ev71 infection]. | to investigate the characteristics of molecular epidemiology and molecular evolution of 5 ev 71 (enterovirus 71, ev71) strains from 5 shenzhen patients with hand-food-mouth disease associated with ev 71 infection. | 2011 | 21789856 |