| role of deer in the epizootiology of babesia microti in massachusetts, usa. | | 1979 | 544828 |
| human babesiosis on nantucket island. clinical features. | between 20 july and 15 octoboer 1975, five cases of human infection with babesia microti were diagnosed on nantucket island, massachusetts. the illness was characterized by fever, drenching sweats, shaking chills, myalgia, arthralgia, extreme fatigue, and a mild-to-moderate hemolytic anemia. none of the patients had a history of splenetomy. although all patients responded symptomatically to treatment with oral chloroquine phosphate, parasitemia and fatigue frequently persisted for several weeks ... | 1977 | 556920 |
| short-tailed shrews as reservoirs of the agents of lyme disease and human babesiosis. | to determine whether short-tailed shrews (blarina brevicauda) serve as reservoir hosts for the lyme disease spirochete (borrelia burgdorferi) and the agent of human babesiosis (babesia microti), we examined nymphal ticks that had fed as larvae on shrews collected from 3 enzootic sites in coastal massachusetts for evidence of infection by either or both of these agents. xenodiagnosis indicated that 11 of 14 shrews were infected by b. burgdorferi. one of 3 piroplasm-infected shrews also infected t ... | 1990 | 2213411 |
| comparative prevalence of babesia microti and borrelia burgdorferi in four populations of ixodes dammini in eastern massachusetts. | we determined the prevalence of babesia microti and borrelia burgdorferi in four populations of ixodes dammini in eastern massachusetts. the feulgen's reaction was more sensitive than the giemsa method for detecting salivarian babesia. a combination of darkfield and direct-fluorescent-antibody examination proved more sensitive than either method alone for detecting spirochetal infection. the prevalence of spirochetes was greater than the prevalence of babesia in each of the tick populations stud ... | 1986 | 2430433 |
| absence of spirochaetes (borrelia burgdorferi) and piroplasms (babesia microti) in deer ticks (ixodes dammini) parasitized by chalcid wasps (hunterellus hookeri). | an entomophagous wasp (hunterellus hookeri howard) parasitizes about a third of the host-seeking nymphal ixodes dammini spielman et al. ticks on naushon island in massachusetts (u.s.a.) where the agents of lyme disease (borrelia burgdorferi johnson et al.) and human babesiosis (babesia microti franca) are enzootic. following blood-feeding, wasp-parasitized ticks are destroyed by the developing wasp. the prevalence of either human pathogen in host-seeking ticks collected in wasp-infested sites is ... | 1987 | 2979518 |
| seasonal variation of transmission risk of lyme disease and human babesiosis. | the seasonal host-seeking pattern of nymphal ixodes dammini infected with babesia microti or borrelia burgdorferi was determined on nantucket island, massachusetts, during 1985. the peak period of host-seeking by infected nymphal i. dammini occurred in may and june. on a per person-hour basis, the number of infected ticks collected reached a maximum in may (babesia = 17.3; borrelia = 16.2). the number of infected ticks remained high in june, but decreased notably in july, august, and september. ... | 1987 | 3687924 |
| vectorial capacity of north american ixodes ticks. | ixodes dammini, the vector of lyme disease and babesiosis, is distributed in various locations in the northeastern quadrant of the united states and nearby canada. the life cycle of this tick, which includes larval, nymphal, and adult stages, spans at least two years. the tick over-winters between larval and nymphal feeding. horizontal transmission of pathogens is facilitated by a feeding pattern in which both the larval and nymphal stages feed on the white-footed mouse, peromyscus leucopus, and ... | 1984 | 6516453 |
| reservoir hosts of human babesiosis on nantucket island. | the host range of babesia microti was studied on nantucket island in order to identify the enzootic reservoir of this human pathogen. white-footed mice (peromyscus leucopus) were more frequently parasitized than were other indigenous animals. infection was ubiquitous in locations where deer were abundant. mice were most frequently parasitemic during spring and summer and adults more frequently than juveniles. parasitemia, which was rarely intense, was sustained for as long as 4 months. mice live ... | 1981 | 7020449 |
| babesiosis in post-splenectomy hosts. | two persons who had been splenectomized later contracted babesiosis, one on cape cod and one near islip, long island, areas where human cases of babesiosis had not been previously identified. one of the patients received pentamidine, but parasitemia persisted after therapy. no deaths have been recorded for persons who had had splenectomies and were later infected with babesia microti. until more effective therapy is available, such patients should be treated conservatively. | 1980 | 7192058 |
| epidemiology of human babesiosis on nantucket island. | between 1969 and 1977, 14 persons with parasitologically confirmed babesia microti infections and seven persons with antibody titers to b. microti greater than or equal to 1:1,024 were identified on nantucket island, massachusetts. nineteen of these 21 persons were interviewed. about half were permanent residents of nantucket; the others spent most of their summers on the island. there were 12 women and seven men. patients ranged in age from 23 to 86 years; all of those with parasitologically co ... | 1981 | 7283012 |
| human babesiosis on nantucket island: prevalence of babesia microti in ticks. | in order to derive direct evidence implicating ixodes dammini as a vector of human babesiosis, we determined the prevalence of babesia microti infection in nymphal i. dammini collected on nantucket island. in experiments in the laboratory we found that nymphs remained attached to hamsters for about 3 days. babesial infection was transmitted more often during 54 hours of attachment then during 36 or 48 hours. since parasites were demonstrable in salivary glands solely after 48 hours, we derived a ... | 1980 | 7435782 |
| cosegregation of a novel bartonella species with borrelia burgdorferi and babesia microti in peromyscus leucopus. | during surveillance for various tickborne pathogens in the upper midwest during the summer and early fall of 1995, a bartonella-like agent was detected in the blood of mice that were concurrently infected with borrelia burgdorferi or babesia microti (or both). the organism was isolated in pure culture after inoculation of blood from wild-caught mice into c.b-17 scid/scid mice. phylogenetic analysis of the 16s rrna and the citrate synthase genes showed that the novel bartonella species and a bart ... | 1998 | 9466529 |
| diversity of babesia infecting deer ticks (ixodes dammini). | to determine whether the presence of nonpathogenic piroplasms may confound field estimates of risk of babesia microti infection, we identified sporozoites infecting the salivary glands of deer ticks (ixodes dammini) by parallel microscopy and polymerase chain reaction assays. piroplasms were evident in 14.4% of adult ticks from sites in the northcentral and northeastern united states. of these, 83.3% contained dna characteristic of ba. odocoilei. this cervid piroplasm was detected in all of the ... | 1998 | 9660456 |
| transmission of babesia microti by blood transfusion in texas. | in the usa, seasonal tickborne transmission of babesia microti occurs in the northeast and upper midwest. a resident of texas became infected through a red blood cell transfusion from an asymptomatic local donor who had summered in massachusetts. the patient's infection was diagnosed by blood smear examination in january, 7 weeks post-transfusion. he died 1 week later from variceal haemorrhage complicated by haemolysis. premortem patient specimens and archived blood from the donor unit tested po ... | 2008 | 19138264 |
| seroprevalence of babesia microti in blood donors from babesia-endemic areas of the northeastern united states: 2000 through 2007. | current estimates of 70 cases of transfusion-transmitted babesia microti, with 12 associated deaths, suggest that babesia is a growing blood safety concern. the extent of babesia infections among blood donors has not been well defined. to determine how common exposure to b. microti is among blood donors, a seroprevalence study was undertaken in the american red cross northeast division. | 2009 | 19821951 |
| not "out of nantucket": babesia microti in southern new england comprises at least two major populations. | deer tick-transmitted human babesiosis due to babesia microti appears to be expanding its distribution and prevalence in the northeastern united states. one hypothesis for this emergence is the introduction of parasites into new sites from areas of long-standing transmission, such as nantucket island, massachusetts. | 2014 | 25492628 |
| passive surveillance of ixodes scapularis (say), their biting activity, and associated pathogens in massachusetts. | a passive surveillance of tick-borne pathogens was conducted over a 7-year period (2006-2012), in which a total of 3551 ticks were submitted to the university of massachusetts for pcr testing. the vast majority of these ticks were ixodes scapularis from massachusetts (n = 2088) and hence were the focus of further analysis. two taqman duplex qpcr assays were developed to test i. scapularis ticks for the presence of three human pathogens: borrelia burgdorferi, anaplasma phagocytophilum, and babesi ... | 2016 | 27248292 |
| severe babesiosis presenting as acute respiratory distress syndrome in an immunocompetent patient. | babesiosis is a tick-borne illness caused by the intraerythrocytic parasite babesia microti. adult respiratory distress syndrome (ards) is a complication of b. microti infection and generally presents later in the course of the disease. we present a case of babesiosis presenting with ards. a 59-year-old male with history of hypertension and atrial fibrillation presented with one day of progressive shortness of breath. the patient returned from a trip to massachusetts one day prior. on arrival to ... | 2014 | 24974563 |