effect of partial substitution of invert sugar for sucrose in combination with duraphat treatment on caries development in preschool children: the malmö study. | the aim was to study the effect of substitution of invert sugar for sucrose, in combination with fluoride varnish (duraphat) treatment twice a year, on caries development in preschool children. one hundred and eighty-seven 4-years-olds were divided randomly into four sugar groups: (1) sucrose (s), (2) sucrose-duraphat (sd), (3) invert sugar (i), and (4) invert sugar-duraphat (id). all families were asked to buy beverages, biscuits, breakfast cereals, marmalade, ice cream, jam, ketchup, sweets an ... | 1991 | 1913770 |