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antimicrobial resistance among gram-negative bacteria isolated from intensive care units in a cardiology institute in istanbul, turkey.antibiotic resistance among gram-negative rods (gnrs) causing hospital-acquired infections poses a threat, particularly to intensive care unit (icu) patients. this study was undertaken in order to achieve the following: to detect the frequency of gnrs isolated from coronary and surgical icus at the institute of cardiology, istanbul university, between january 2000-december 2002; to compare the resistance of these gnrs to selected antibiotics; and to determine the prevalence of extended-spectrum ...200516116256
increasing carbapenem resistance due to the clonal dissemination of oxacillinase (oxa-23 and oxa-58)-producing acinetobacter baumannii: report from the turkish sentry program sites.a significant increase in carbapenem-resistance rates among acinetobacter baumannii isolates collected in two turkish medical centres was detected in the 2000-2006 period (20-60 %) by the sentry antimicrobial surveillance program. carbapenem-resistant strains from 2006 were evaluated for the presence of encoding genes and epidemic clonality. oxa-58-like and oxa-23-like carbapenemase-producing strains were detected in both medical institutions. seventeen out of 18 strains from ankara were positiv ...200819018025
spread of carbapenem-resistant international clones of acinetobacter baumannii in turkey and azerbaijan: a collaborative study.epidemic clones of acinetobacter baumannii, described as european clones i, ii, and iii, are associated with hospital epidemics throughout the world. we aimed to determine the molecular characteristics and genetic diversity between european clones i, ii, and iii from turkey and azerbaijan. in this study, a total of 112 bloodstream isolates of carbapenem-resistant acinetobacter spp. were collected from 11 hospitals across turkey and azerbaijan. the identification of acinetobacter spp. using conve ...201627259712
oxa-type carbapenemases and susceptibility of colistin and tigecycline among carbapenem-resistant acinetobacter baumannii isolates from patients with bacteremia in turkey.carbapenem-resistant acinetobacter baumannii (crab) has emerged as one of the most troublesome pathogens in healthcare settings worldwide. the present study was conducted to analyze the genes encoding resistance to carbapenems and to determine in vitro activity of colistin and tigecycline against crab isolates from blood culture of hospitalized patients at istanbul university cerrahpasa medical school hospital.201526299073
[investigation of the frequency and distribution of beta-lactamase genes in the clinical isolates of acinetobacter baumannii collected from different regions of turkey: a multicenter study].the diversity and distribution of tem, shv and ctx-m type of extended-spectrum beta-lactamases (esbls) are important for the treatment and control of infections. determination of esbl genes in clinical isolates by polymerase chain reaction (pcr) and dna sequencing can obtain useful data for their molecular epidemiology and risk. the aim of this study was to investigate the frequency of beta-lactamase genes in acinetobacter baumannii strains isolated from different regions of turkey. a total of 5 ...201628124956
oxa- and ges-type β-lactamases predominate in extensively drug-resistant acinetobacter baumannii isolates from a turkish university hospital.we determined the antibiotic susceptibility and genetic mechanisms of resistance in clinical strains of acinetobacter baumannii from istanbul, turkey. a total of 101 clinical strains were collected between november 2011 and july 2012. antimicrobial susceptibility was performed using the vitek 2 compact system and e-test. multiplex pcr was used for detecting bla(oxa -51-like), bla(oxa -23-like), bla(oxa -40-like) and bla(oxa -58-like) genes. isaba1, bla(imp -like), bla(vim -like), bla(ges), bla(v ...201423957892
[distribution of blaoxa genes in acinetobacter baumannii strains: a multicenter study].acinetobacter baumannii is the most important agent of nosocomial infections within the acinetobacter genus. this gram-negative coccobacillus is intrinsically resistant to many antibiotics used in antimicrobial therapy, and capable of developing resistance including carbapenems. the objective of this study was to develop a multiplex real time polymerase chain reaction (qpcr) kit for oxa subgroups in a.baumannii, and to investigate the distribution of oxa subgroups in a.baumannii strains isolated ...201324237428
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