| [the journey of legionella pneumophila from amoebae to macrophage. reflections on the largest outbreak of legionnaire's disease]. | legionella, the causative agent of legionnaire's disease (ld), can survive and grow in amoebic cells. free-living amoebae may play a role in the selection of virulence traits and in adaptation to survival in macrophages, and represent an important reservoir of legionella. these amoebae may act as a trojan horse bringing hidden bacteria within the human environments. the community outbreak of ld that occurred in murcia in july 2001, the largest such outbreak ever reported, afforded an unusual opp ... | 2005 | 16524240 |
| legionnaires' disease outbreak in murcia, spain. | an explosive outbreak of legionnaires' disease occurred in murcia, spain, in july 2001. more than 800 suspected cases were reported; 449 these cases were confirmed, which made this the world's largest outbreak of the disease reported to date. dates of onset for confirmed cases ranged from june 26 to july 19, with a case-fatality rate of 1%. the epidemic curve and geographic pattern from the 600 competed epidemiologic questionnaires indicated an outdoor point-source exposure in the northern part ... | 2003 | 12967487 |