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changing etiology of bacteremia in patients with hematological malignancies in denmark.to ascertain whether the microbiological etiology of bacteremia among patients with hematological malignancies has changed in denmark, the species distribution of clinically relevant blood culture isolates from the hematological department at rigshospitalet, copenhagen in 1990 was compared with 2 previous studies (1970-72; 1981-85). in addition, time trends of the etiology of bacteremia among hematological patients in copenhagen (eastern denmark) and in arhus (western denmark) were compared. in ...19948036471
long-term survival and nutritional data in patients with cystic fibrosis treated in a danish centre.adequate nutrition and optimal treatment of bronchopulmonary infections are both of critical importance in maintaining the health of patients with cystic fibrosis. the cystic fibrosis centre in copenhagen has followed a regimen of very early and aggressive antimicrobial treatment, especially against pseudomonas aeruginosa infection. an unrestricted diet of low fat and high protein without hyperalimentation was recommended before 1985 which was then changed to a high fat, high calorie intake.19968977604
molecular epidemiology and dynamics of pseudomonas aeruginosa populations in lungs of cystic fibrosis patients.the ability to establish lifelong persistent infections is a fundamental aspect of the interactions between many pathogenic microorganisms and their mammalian hosts. one example is chronic lung infections by the opportunistic pathogen pseudomonas aeruginosa in cystic fibrosis (cf) patients. this infection process is associated with extensive genetic adaptation and microevolution of the infecting bacteria. through investigations of p. aeruginosa populations and infection dynamics in a group of cf ...200717261614
differences in prevalence and treatment of pseudomonas aeruginosa in cystic fibrosis centres in denmark, norway and sweden.chronic pseudomonas aeruginosa (pa) infection causes increased morbidity and mortality in cystic fibrosis (cf). this study aimed to answer the following questions: does the prevalence of chronic infection with pa differ between the cf centres in scandinavia? which differences exist concerning segregation and treatment of pa?200919157995
long-term, low-dose azithromycin treatment reduces the incidence but increases macrolide resistance in staphylococcus aureus in danish cf patients.since 2001, long-term, low-dose azithromycin treatment has been used for cf patients chronically infected with pseudomonas aeruginosa in the copenhagen cf centre. our study investigates changes in incidence of colonization with staphylococcus aureus, streptococcus pneumoniae, haemophilus influenzae and moraxella catarrhalis and changes in macrolide sensitivity in these microorganisms during azithromycin treatment.200918849202
pseudomonas aeruginosa and burkholderia cepacia infection in cystic fibrosis patients treated in toronto and copenhagen.differences in the course of pulmonary disease in cystic fibrosis (cf) may be altered by different treatment strategies in different cf centers. the copenhagen clinic uses scheduled, regular and very aggressive treatment of lung infection. the toronto clinic treats pulmonary infection with oral, inhaled, or intravenous antibiotics, and has emphasized aggressive nutritional therapy. this study compared the clinical status of cf patients treated in the two centers (toronto, canada, n=302, and cope ...19989727758
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