| crimean-congo hemorrhagic fever: experience at a tertiary care hospital in karachi, pakistan. | crimean-congo hemorrhagic fever (cchf) is endemic in certain rural areas of pakistan. since the discovery of cchf virus (cchfv) in the country in the 1960s, there have been 13 outbreaks in addition to sporadic cases. an outbreak during 2000 coincided with the movement of sacrificial animals from rural to urban areas for the festival of eid-ul-azha. diagnosis was suspected in patients with fever and thrombocytopenia, and confirmed retrospectively using immunoassays and reverse transcriptase-pcr. ... | 2005 | 15935414 |
| short report: diagnostic testing for hemorrhagic fevers in pakistan: 2007-2013. | crimean-congo hemorrhagic fever virus (cchfv) and dengue virus (denv) are endemic to pakistan. patients presenting with symptoms of fever, bleeding, and rash cannot be distinguished without appropriate testing. we report data on 354 samples tested for cchfv at the aga khan university hospital in pakistan between 2007 and 2013. all samples were tested for the presence of cchfv rna. some samples were also tested for denv rna, ns-1 antigen, and/or reactive immunoglobulin m antibodies. of 354 clinic ... | 2014 | 25311694 |
| crimean-congo hemorrhagic fever: prevention and control limitations in a resource-poor country. | in autumn 2000, an outbreak of crimean-congo hemorrhagic fever (cchf) occurred in pakistan and involved nosocomial cases due to human-to-human transmission at a tertiary care hospital in karachi. during a hospital-based investigation, 6 serologically confirmed cases (i.e., patients seropositive for cchf antigen or anti-cchf immunoglobulin m antibodies by means of a capture enzyme-linked immunosorbent assay [elisa]) and 3 clinically confirmed cases (i.e., patients with negative elisa for cchf but ... | 2004 | 15227619 |