| transmission ecosystems of echinococcus multilocularis in china and central asia. | from continental to regional scales, the zoonosis alveolar echinococcosis (ae) (caused by echinococcus multilocularis) forms discrete patches of endemicity within which transmission hotspots of much larger prevalence may occur. since the late 80s, a number of hotspots have been identified in continental asia, mostly in china, wherein the ecology of intermediate host communities has been described. this is the case in south gansu, at the eastern border of the tibetan plateau, in south ningxia, in ... | 2013 | 23734823 |
| a newly discovered epidemic area of echinococcus multilocularis in west gansu province in china. | alveolar echinococcosis (ae) is a lethal parasitic disease. in gansu province of china, all ae cases reported in literature were from zhang and min counties, the southern part of the province. here, we report the discovery of nine ae cases and one cystic echinococcosis (ce) case from nanfeng town of minle county, in the middle of hexi corridor in west gansu province. the diagnosis of these cases were confirmed by serology, histopathology, computed tomography, b-ultrasound, immunohistochemistry m ... | 2015 | 26186219 |
| landscape composition and spatial prediction of alveolar echinococcosis in southern ningxia, china. | alveolar echinococcosis (ae) presents a serious public health challenge within china. mass screening ultrasound surveys can detect pre-symptomatic ae, but targeting areas identified from hospital records is inefficient regarding ae. prediction of undetected or emerging hotspots would increase detection rates. voles and lemmings of the subfamily arvicolinae are important intermediate hosts in sylvatic transmission systems. their populations reach high densities in productive grasslands where food ... | 2008 | 18846237 |
| spatial modelling and ecology of echinococcus multilocularis transmission in china. | recent research in central china has suggested that the most likely transmission mechanism for echinococcus multilocularis to humans is via domestic dogs which are allowed to roam freely and hunt (infected) small mammals within areas close to villages or in areas of tented pasture. this assertion has led to the hypothesis that there is a landscape control on transmission risk since the proximity of suitable habitat for susceptible small mammals appears to be the key. we have tested this hypothes ... | 2006 | 16371253 |
| transmission ecology of echinococcus multilocularis: what are the ranges of parasite stability among various host communities in china? | a striking feature of the transmission ecology of echinococcus multilocularis in china is the diversity of hosts that contribute to the parasite cycle. considering the population dynamics of key reservoir intermediate hosts and the ratio of their preferred habitat in a landscape (rompa) is essential to understanding transmission, but the numerous communities in which the parasite cycles and the extent of those communities is currently far from being fully documented. on the tibetan plateau grass ... | 2006 | 16361111 |
| molecular study of echinococcus in west-central china. | west-central china is an important endemic focus of both alveolar and cystic echinococcosis where several species of intermediate host are commonly infected with echinococcus granulosus and e. multilocularis . isolates of e. granulosus were collected from humans and other animals from different geographical areas of qinghai, ningxia, gansu and sichuan, and genotyped using the mitochondrial dna marker atp synthase subunit 6 gene (atp6). the sheep strain (g1 genotype) of e. granulosus was shown to ... | 2005 | 16174420 |
| ecological epidemiology: landscape metrics and human alveolar echinococossis. | the larval form of the fox tapeworm echinococcus multilocularis can cause a potentially fatal liver infection in human hosts. globally rare, the disease has a high prevalence focus in western china. recent research has linked landscape to the presence and prevalence of the disease. this paper discusses the epidemiology of e. multilocularis in terms of landscape and disease transmission ecology. landscape form was defined using satellite imagery to create a land cover classification for a study s ... | 2004 | 15246932 |
| epidemiology of alveolar echinococcosis with particular reference to china and europe. | human alveolar echinococcosis (ae), caused by the metacestode of the fox tapeworm echinococcus multilocularis, is the most pathogenic zoonosis in temperate and arctic regions of the northern hemisphere. prospective collection of human cases in some areas and mass screenings using ultrasound imaging and confirmation with serological techniques have markedly improved our knowledge of the epidemiology of the disease in humans during the past two decades. transmission occurs when eggs of the tapewor ... | 2003 | 15027607 |
| combined ultrasound and serologic screening for hepatic alveolar echinococcosis in central china. | alveolar echinococcosis (ae), caused by echinococcus multilocularis, is a zoonotic helminthic disease that can mimic malignancy. in the 1970s, foci of the disease were found in central china. the aim of the present study was to estimate the prevalence of ae in humans in 2 districts of south gansu province, china, by use of ultrasound and echinococcus serology. after answering an epidemiological questionnaire, 2,482 volunteers from 28 villages underwent ultrasound. serology via enzyme-linked immu ... | 2002 | 12135263 |
| an epidemiological and ecological study of human alveolar echinococcosis transmission in south gansu, china. | human alveolar echinococcosis (ae) is usually a rare, highly pathogenic zoonotic disease, transmitted across the northern hemisphere between fox and rodent hosts. in china the first cases were described in 1965; however very few epidemiological studies have been undertaken since. following identification in 1991 of a serious focus of human ae in south gansu province, detailed village-based community and ecological studies were carried out between 1994 and 1997. hepatic ultrasound mass screening ... | 2000 | 11080507 |
| karyological and dental identification of microtus limnophilus in a large focus of alveolar echinococcosis (gansu, china). | a study of voles (arvicolidae, rodentia) from gansu (china) designed to identify a potential host of echinococcus multilocularis, responsible for human alveolar echinococcosis, leads to a general analysis of microtus limnophilus population karyotypes, m1 of m. oeconomus populations from all of eurasia and of m. limnophilus of mongolia. the microtus of gansu belonging to the nominal subspecies m. limnophilus limnophilus (2n = 38; nf = 58) differs markedly in size and shape of m1 from the m. limno ... | 1999 | 10457599 |
| a large focus of alveolar echinococcosis in central china. | human alveolar echinococcosis (ae) is a rare and highly pathogenic helminthic zoonosis due to infection with the intermediate stage of the small fox tapeworm, echinococcus multilocularis. parasite transmission is restricted to northern latitudes, including central and north china, from where few clinical and no detailed community studies have been reported. in august, 1991, 65 (5%) of 1312 people residing in three rural communes of zhang county, gansu province, china were diagnosed as having hep ... | 1992 | 1357252 |