Publications

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epidemiology of alveolar echinococcosis with particular reference to china and europe.human alveolar echinococcosis (ae), caused by the metacestode of the fox tapeworm echinococcus multilocularis, is the most pathogenic zoonosis in temperate and arctic regions of the northern hemisphere. prospective collection of human cases in some areas and mass screenings using ultrasound imaging and confirmation with serological techniques have markedly improved our knowledge of the epidemiology of the disease in humans during the past two decades. transmission occurs when eggs of the tapewor ...200315027607
molecular study of echinococcus in west-central china.west-central china is an important endemic focus of both alveolar and cystic echinococcosis where several species of intermediate host are commonly infected with echinococcus granulosus and e. multilocularis . isolates of e. granulosus were collected from humans and other animals from different geographical areas of qinghai, ningxia, gansu and sichuan, and genotyped using the mitochondrial dna marker atp synthase subunit 6 gene (atp6). the sheep strain (g1 genotype) of e. granulosus was shown to ...200516174420
simultaneous alveolar and cystic echinococcosis of the liver.alveolar echinococcosis (ae) and cystic echinococcosis (ce), caused by infection with the larval stages of echinococcus multilocularis and e. granulosus, respectively, are of major clinical importance. reports of infection with ae or ce are very common, but instances of simultaneous or dual infection are rare. we report on four cases with mixed ae/ce infections in the liver, diagnosed using retrospective surgical records and active community surveys in southern ningxia hui autonomous region (nha ...200616336985
transmission ecology of echinococcus multilocularis: what are the ranges of parasite stability among various host communities in china?a striking feature of the transmission ecology of echinococcus multilocularis in china is the diversity of hosts that contribute to the parasite cycle. considering the population dynamics of key reservoir intermediate hosts and the ratio of their preferred habitat in a landscape (rompa) is essential to understanding transmission, but the numerous communities in which the parasite cycles and the extent of those communities is currently far from being fully documented. on the tibetan plateau grass ...200616361111
unique family clustering of human echinococcosis cases in a chinese community.we have identified a significant focus and unusual clustering of human cases of cystic echinococcosis (ce) and alveolar echinococcosis (ae) in the village of nanwan, xiji county, ningxia hui autonomous region, in one of the most highly endemic areas for both diseases in china. the village, a chinese hui islamic community, is composed of 167 members of four extended families. a total of 28 people died (12 of echinococcosis) since the village was first settled in the 1950s. despite similar life pa ...200616525111
community surveys and risk factor analysis of human alveolar and cystic echinococcosis in ningxia hui autonomous region, china.to determine the true community prevalence of human cystic (ce) and alveolar (ae) echinococcosis (hydatid disease) in a highly endemic region in ningxia hui, china, by detecting asymptomatic cases.200617128341
echinococcosis in ningxia hui autonomous region, northwest china.cystic echinococcosis (ce), caused by echinococcus granulosus, and alveolar echinococcosis (ae), due to e. multilocularis, are endemic to large areas of north and northwest china. here we review features of a severe focus of ae and ce in ningxia hui autonomous region (nhar), northwest china. we describe for nhar the results of surveys of hospital surgical and clinical records, including treatment of ae and ce, and active community detection of asymptomatic/early-stage cases and patient follow-up ...200818314150
landscape composition and spatial prediction of alveolar echinococcosis in southern ningxia, china.alveolar echinococcosis (ae) presents a serious public health challenge within china. mass screening ultrasound surveys can detect pre-symptomatic ae, but targeting areas identified from hospital records is inefficient regarding ae. prediction of undetected or emerging hotspots would increase detection rates. voles and lemmings of the subfamily arvicolinae are important intermediate hosts in sylvatic transmission systems. their populations reach high densities in productive grasslands where food ...200818846237
transmission ecosystems of echinococcus multilocularis in china and central asia.from continental to regional scales, the zoonosis alveolar echinococcosis (ae) (caused by echinococcus multilocularis) forms discrete patches of endemicity within which transmission hotspots of much larger prevalence may occur. since the late 80s, a number of hotspots have been identified in continental asia, mostly in china, wherein the ecology of intermediate host communities has been described. this is the case in south gansu, at the eastern border of the tibetan plateau, in south ningxia, in ...201323734823
serological prevalence of echinococcosis and risk factors for infection among children in rural communities of southern ningxia, china.to assess the usefulness of serology as an indicator of echinococcus transmission for developing preventive measures against echinococcosis in rural communities.200818554249
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