| neurovirulence in mice of h5n1 influenza virus genotypes isolated from hong kong poultry in 2001. | we studied the pathogenicity of five different genotypes (a to e) of highly pathogenic avian h5n1 viruses, which contained ha genes similar to those of the h5n1 virus a/goose/guangdong/1/96 and five different combinations of "internal" genes, in a mouse model. highly pathogenic, neurotropic variants of genotypes a, c, d, and e were isolated from the brain after a single intranasal passage in mice. genotype b virus was isolated from lungs only. the mouse brain variants had amino acid changes in a ... | 2003 | 12610156 |
| ehrlichia-like organism gene found in small mammals in the suburban district of guangzhou of china. | the 16s rrna gene of ehrlichia genus was examined from the blood and spleen of 26 wild small mammals that were captured at a canine feed lot where the first case of canine ehrlichiosis was found in south of china in 1998. samples (3 blood and 1 spleen) from rattus norvegicus were positive by polymerase chain reaction. the amplimers were then cloned and sequenced. all of the 16s rrna gene sequence of these samples were found to be same and unique when compared with the other members of genus ehrl ... | 2003 | 12860609 |
| [study on the epidemiological characteristics and natural infectious focus of angiostrongylus cantonensis in shenzhen area of zhujiang delta in china]. | to delimit the natural infectious focus, including the distribution of wildlife, species, ecology of intermediate hosts and final host of angiostrongylus cantonensis, as well as the routes of transmission and epidemiological characteristics and wildlife of human angiostrongylus cantonensis, based on human diverging cases identified in shenzhen, southern area of china. | 2008 | 19040040 |
| [survey on the focus of angiostrongylus cantonensis in guangdong province]. | to understand the distribution of angiostrongylus cantonensis foci in guangdong province for making surveillance program. | 2010 | 20411741 |
| [analysis of paralytic shellfish poison of bivalves in seafood market in guangzhou]. | the investigations of the paralytic shellfish poisoning (psp) from huangsha seafood market of guangzhou was performed to assess the risk of psp in bivalves. | 2005 | 15862036 |
| [analyzing genetic quality of balb/c mouse strains in china by microsatellite marking]. | eleven balb/c mouse strains of beijing, shanghai, shenyang, haerbin, guangzhou, chongqing and changchun were monitored in order to assure the genetic quality of inbred balb/c mouse strains in china and to estimate the credibility of microsatllite markers. fourteen microsatellites loci on different chromosomes were investigated by pcr analysis. it showed that all these microsatellites dna loci displayed single allelic gene band in mouse strains of beijing, shanghai and haerbin. but the mice came ... | 2004 | 15762004 |
| [isolation, identification and sequence analyses of dengue virus type 2 strain gd19/2001]. | to identify the virus isolated from jiangmen, guangdong province and to discuss the possible origin. | 2003 | 12820947 |
| generation and evaluation of a high-growth reassortant h9n2 influenza a virus as a pandemic vaccine candidate. | h9n2 subtype avian influenza viruses (aivs) are widely distributed in avian species and were isolated from humans in hong kong and guangdong province, china in 1999 raising concern of their potential for pandemic spread. we generated a high-growth reassortant virus (g9/pr8) that contains the hemagglutinin (ha) and neuraminidase (na) genes from the h9n2 avian influenza virus a/chicken/hong kong/g9/97 (g9) and six internal genes from a/puerto rico/8/34 (pr8) by genetic reassortment, for evaluation ... | 2003 | 12706686 |
| First provincial survey of Angiostrongylus cantonensis in Guangdong Province, China. | The rat lungworm Angiostrongylus cantonensis is a zoonotic nematode with a wide distribution. We report the first provincial survey of the prevalence of A. cantonensis infection among wild rodents and snails in Guangdong Province, China. A total of 2929 Pomacea canaliculata and 1354 Achatina fulica were collected from fields in 22 survey sites with a larval infection rates ranging from 0-26.6% to 0-45.4%. In addition, 114 Cipangopaludina sp and 252 Bellamya sp were bought from markets; larvae we ... | 2011 | 21906215 |
| epidemiological survey of angiostrongylus cantonensis in the west-central region of guangdong province, china. | the study was to understand the angiostrongylus cantonensis infectious situation of rodent definitive host, snail intermediate host, and local residents in the west-central region of guangdong province in china. the snails achatina fulica and pomacea canaliculata collected from the survey place were digested with artificial gastric juice, and the third-stage larvae of a. cantonensis in the snails were examined under microscope. the heart and lung of rats captured from the survey place were taken ... | 2011 | 21301874 |
| mdm2 promoter snp309 is associated with risk of occurrence and advanced lymph node metastasis of nasopharyngeal carcinoma in chinese population. | mouse double minute 2 (mdm2) is a key negative regulator of the p53 activity. recently, a polymorphism in the mdm2 intronic promoter, snp309, was shown to influence mdm2 expression and p53 activity. we examined whether the snp309 was related to the risk of developing nasopharyngeal carcinoma (npc) among chinese populations. | 2007 | 17473193 |