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genetic clustering of borna disease virus natural animal isolates, laboratory and vaccine strains strongly reflects their regional geographical origin.the aim of this study was to gain more detailed insights into the genetic evolution and variability of borna disease virus (bdv). phylogenetic analyses were performed on field viruses originating from naturally infected animals, the bdv vaccine strain 'dessau', four widely used laboratory strains and the novel bdv subtype no/98. four regions of the bdv genome were analysed: the complete p40, p10 and p24 genes and the 5'-untranslated region of the x/p transcript. bdv isolates from the same geogra ...200515659758
[borna disease in switzerland and in the principality of liechtenstein].borna disease (bd) is a rare immunopathological disorder of the central nervous system (cns) caused by infection with borna disease virus (bdv) and histologically characterized by mononuclear encephalomyelitis. bd primarily affects equines and sheep in well defined endemic areas of central europe, but bdv infections have also been reported in other host species including humans, as well as in non endemic regions. in this paper recent data on the pathogenesis of bd are reviewed and the current si ...199910596273
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