| malaria in aberdeen: an audit of 110 patients admitted between 1980-1991. | all 110 patients seen in north east scotland after contracting malaria from foreign travel were treated in the regional infection unit in aberdeen. those patients managed there from january 1980 to march 1991 are described. there were 54 episodes of plasmodium falciparum malaria (49%) and 26 episodes (23%) of plasmodium vivax malaria. the remainder had either mixed infection or were diagnosed as malaria on high clinical probability. the majority of the patients were male (80%) and under 40 years ... | 1992 | 1411477 |
| changing patterns of malaria in south-east scotland: implications for practitioner awareness and prophylactic advice. | the medical records of all 229 patients with malaria admitted to the edinburgh city hospital between 1969 and 1988 were studied retrospectively. a total of 137 were from africa, 44 from the indian subcontinent, 19 from the far east, 18 from new guinea, 5 from the middle east and 3 from south america. the number of yearly admissions rose markedly after 1983, mainly due to an increase in plasmodium falciparum cases. ninety-four cases (15 with severe parasitaemia) mainly from kenya and nigeria were ... | 1992 | 1561183 |
| childhood malaria in edinburgh 1961-1982. | forty one cases of malaria in children less than 15 years of age were identified from the records of edinburgh hospitals between 1961 and 1982. annually children constitute 10 to 20 per cent of all cases of malaria in scotland and since 1971 at least one case has been admitted to an edinburgh paediatric unit every year. non-immune children visiting relatives in the indian sub-continent are the largest group at risk. prophylaxis was not usually taken by the patients visiting asia and the cases fr ... | 1983 | 6359413 |
| information about antimalarial chemoprophylaxis in hospitalised patients--is it adequate? | malaria remains a huge public health problem worldwide, with over 100 million new cases annually, causing one to two million deaths. this global problem spills over into the uk, with around 2000 cases of reported annually. the proportion of infections due to plasmodium falciparum (pf) continues to increase and worse still accounts for five to 12 deaths per year. in 1992, nathwani et al reported the 10 year experience of malaria cases admitted to the regional infection unit, in aberdeen, scotland ... | 1997 | 9226772 |
| changes in cytokine production associated with acquired immunity to plasmodium falciparum malaria. | individuals living in malaria-endemic areas eventually develop clinical immunity to plasmodium falciparum. that is, they are able to limit blood parasite densities to extremely low levels and fail to show symptoms of infection. as the clinical symptoms of malaria infection are mediated in part by pro-inflammatory cytokines it is not clear whether the acquisition of clinical immunity is due simply to the development of antiparasitic mechanisms or whether the ability to regulate inflammatory cytok ... | 2001 | 11737069 |
| choice of and adherence to prophylactic antimalarials. | there were 1,370 cases of imported malaria and six fatalities in the uk in 2008, the majority of which were due to chloroquine-resistant plasmodium falciparum. poor adherence to prescribed regimens is known to be an important factor in these cases. | 2011 | 21722235 |
| imported malaria in scotland--an overview of surveillance, reporting and trends. | imported malaria cases continue to occur and are often underreported. this study assessed reporting of malaria cases and their characteristics in scotland. | 2011 | 22056775 |
| travellers as sentinels: assaying the worldwide distribution of polymorphisms associated with artemisinin combination therapy resistance in plasmodium falciparum using malaria cases imported into scotland. | there is growing evidence that plasmodium falciparum parasites in southeastern asia have developed resistance to artemisinin combination therapy. the resistance phenotype has recently been shown to be associated with four single nucleotide polymorphisms in the parasite's genome. we assessed the prevalence of two of these single nucleotide polymorphisms in p. falciparum parasites imported into scotland between 2009 and 2012, and in additional field samples from six countries in southeastern asia. ... | 2013 | 23899818 |