| [development of chemoresistance of plasmodium falciparum to chloroquine and mefloquine in benin between 1980 and 1989]. | resistance of p. falciparum to chloroquine has been notified in 1986 in non-immune visitors. authors organized surveys of in vivo and in vitro tests to follow evolution of the phenomena. the increase in number of p. falciparum strains resistant to chloroquine was sudden in 1986 but stopped to rise from this date, and even seemed to decrease gently. the geographical distribution of the resistance, restricted to the region of cotonou, could be explained by illegitimate chloroquine distribution. bu ... | 1990 | 2208463 |
| [malaria and sickle-cell anemia. a correlation of the clinical and epidemiological aspects]. | a study was carried out on susceptibility of sicklemia patients to plasmodium falciparum (pf) malaria in 151 hemoglobin s carriers (homozygous and heterozygous), assisted at the cotonú hospital, benin, for 1 year. these diseased did not have any serious malaria complications. the results were compared to a control group without sickle-cell anemia who had 21.5% of complications due to the disease. prevalence of genetic anomaly was higher than 20% among the general population under study. | 1992 | 1344691 |
| [in vivo amodiaquine sensitivity of plasmodium falciparum in the town of cotonou and in the vicinity (bénin)]. | in the coastal area of benin, where chloroquine resistant plasmodium falciparum strains occur, 152 children in the guezo military camp (cotonou) and 448 children in a fishermen village (ekpe), on the southern bank of lake nokoue, are examined. the falciparum malaria infected children (29 and 135 respectively) have received 35 mg/kg body weight of amodiaquine (flavoquine) divided in three consecutive daily doses. only one child among the 69 treated having a parasitemia higher than 1,000/mm3 faile ... | 1990 | 2195282 |
| malaria incidence and prevalence among children living in a peri-urban area on the coast of benin, west africa: a longitudinal study. | clinical malaria incidence was determined over 18 months in a cohort of 553 children living in a peri-urban area near cotonou. three cross-sectional surveys were also carried out. malaria incidence showed a marked seasonal distribution with two peaks: the first corresponding to the long rainy season, and the second corresponding to the overflowing of lake nokoue. the overall plasmodium falciparum incidence rate was estimated at 84/1,000 person-months, and its prevalence was estimated at over 40% ... | 2010 | 20810805 |
| malaria transmission in the lagoon area of cotonou, benin. | a study of the prevalence and intensity of malaria transmission in the lagunar area of benin was carried out by means of repeated cross-sectional surveys of the child population. six areas were selected: two urban areas of cotonou, three lagunar villages and one savanna village. slide positive rates and prevalence of antibodies to p. falciparum sporozoites were examined in june-july 1989 (long rainy season), october-november 1989 (short rainy season) and march-april 1990 (short dry season). para ... | 1992 | 1339969 |
| rapid urban malaria appraisal (ruma) iv: epidemiology of urban malaria in cotonou (benin). | an estimated 40 % of the population in benin lives in urban areas. the purpose of the study was to estimate malaria endemicity and the fraction of malaria-attributable fevers in health facilities in cotonou. | 2006 | 16749927 |
| [no influence of season of transmission nor age of patients on the complexity and genetic diversity of plasmodium falciparum infection in cotonou, benin]. | the aim of the present study was to determine the genetic diversity and allelic frequencies of the genes encoding for the merozoite surface protein-1 (msp-1) and protein-2 (msp-2) of p. falciparum collected from beninese patients during the high and low transmission seasons in cotonou, in south benin. sixty and twenty-four patients were sampled during the dry and wet seasons, respectively parasite dna was analysed using allele-specific primers to amplify block2 of msp-1 and central variable regi ... | 2001 | 16579077 |
| no influence of the transmission season on genetic diversity and complexity of infections in plasmodium falciparum isolates from benin. | the principal goals of the present study were to determine the genetic diversity of the merozoite surface protein-1 (msp-1) and protein-2 (msp-2) genes and the complexity of infections in p. falciparum isolates collected from beninese patients during high and low transmission season at cotonou, in south benin. sixty and twenty-four patients were sampled during dry and wet season respectively. parasite dna was analysed using allele-specific primers to amplify block 2 of msp-1 and central variable ... | 2001 | 14513933 |
| [low levels of chloroquine resistance of plasmodium falciparum in the province of zou in benin]. | an in vivo test using the who protocol (chloroquine 25 mg/kg within 3 days, trial over 7 days) was performed in 72 children in the province of zou, benin, in july-august 1987. the blood concentration of chloroquine was dosed before, during and after treatment by a sensitive method. this study showed a low rate of drug resistance (4.2%), even though surveys in cotonou exhibited a high level of chloroquine resistance. | 1988 | 3052897 |
| [the risk of malaria transmission by blood transfusion at cotonou, benin]. | the risk of transmission of infectious agents by blood transfusion is a permanent preoccupation for diseases that we do not know how to cure, such as hepatitis b, hepatitis c and aids. however, few studies have been carried out concerning the risks of transmitting curable infectious diseases, such as malaria. we carried out a cross-sectional study of 355 healthy blood donors in the rainy season, in which we used thick and thin blood film smears to screen for malaria. we found that 33.5% of donor ... | 2000 | 11226934 |