| new trends in chloroquine efficacy in the treatment of malaria: chloroquine-resistant plasmodium falciparum in anambra and benue states of nigeria. | increasing malaria treatment failures with chloroquine (c25) and reports of chloroquine resistant plasmodium falciparum (crpf) led to the field survey of two sites (agbani and jato-aka) both in primary health zone a, using who--in vivo seven-day test, modified to 14-day follow-up period. of the 922 children studied, high transmission rates of 40 pc and 59.2 pc were found in agbani and jato-aka respectively. varying degrees of parasitologic failures (crpf), 52 pc in agbani and 60 pc in jato-aka w ... | 1991 | 1790563 |
| efficacies of chloroquine and pyrimethamine-sulphadoxine in a nigerian population with chloroquine resistant p. falciparum malaria. | a modification of the standard world health organisation 7--day in vivo test was used to assess the parasitologic and, to limited extent, the clinical response of children less than 5 years of age to defined oral dosages of chloroquine and pyrimethamine-sulphadoxine during the 14 days following the initiation of treatment. the study took place in jato-aka, a rural community in benue state of nigeria. 471 children were screened and 271 (59%) of these had plasmodium parasites thus showing a high t ... | 1990 | 2202586 |