| lack of efficacy of pyrimethamine prophylaxis in pregnant nigerian women. | to evaluate the efficacy of pyrimethamine on the blood stage (suppressive prophylaxis) and liver stage (causal prophylaxis) of plasmodium falciparum in pregnant women, in vivo and in vitro field studies were conducted in ilorin, nigeria, from jan 1 to june 30, 1988. for pregnant women with p falciparum infections who received 25 mg of pyrimethamine weekly for suppressive prophylaxis, 67% (59/88) of in vivo and 60% (6/10) of in vitro tests showed pyrimethamine resistance. a second group of parasi ... | 1989 | 2571759 |
| chloroquine-resistant plasmodium falciparum malaria in ilorin, nigeria: prevalence and risk factors for treatment failure. | presumptive treatment of fever with chloroquine (cq) remains the major strategy for malaria control in nigeria. efficacy surveillance of cq must therefore be continuous for this strategy to remain valid. in this study we determined the efficacy of cq in 120 patients aged 6m to 34yr who presented with acute uncomplicated plasmodium falciparum malaria. clinical success was 86.6%. parasitological cure was 56.7%. mean fever and parasite clearance times were 2.5 +/- 1.2d and 4.2 +/- 1.6d, respectivel ... | 2001 | 14510122 |
| identification of three members of the anopheles funestus (diptera: culicidae) group and their role in malaria transmission in two ecological zones in nigeria. | the role of the anopheles funestus group in malaria transmission was investigated in two ecological zones in nigeria. sampling was carried out at four sites each around ibadan (forest) and ilorin (savanna). human landing catches were supplemented with indoor and outdoor resting collections. pcr was used to identify 1848 a. funestus group mosquitoes to species level (749 in the savanna, 1099 in the forest) and three species were identified. in the forest, a. funestus s.s. predominated (55.4%), fo ... | 2005 | 15869772 |
| co-endemicity of plasmodium falciparum and intestinal helminths infection in school age children in rural communities of kwara state nigeria. | malaria and intestinal helminths co-infection are major public health problems particularly among school age children in nigeria. however the magnitude and possible interactions of these infections remain poorly understood. this study determined the prevalence, impact and possible interaction of plasmodium falciparum and intestinal helminths co-infection among school children in rural communities of kwara state, nigeria. | 2015 | 26222743 |
| population genomics diversity of plasmodium falciparum in malaria patients attending okelele health centre, okelele, ilorin, kwara state, nigeria. | plasmodium falciparum, the most dangerous malaria parasite species to humans remains an important public health concern in okelele, a rural community in ilorin, kwara state, nigeria. there is however little information about the genetic diversity of plasmodium falciparum in nigeria. | 2016 | 27917203 |
| high prevalence of plasmodium falciparum and soil-transmitted helminth co-infections in a periurban community in kwara state, nigeria. | prevalence of malaria and soil-transmitted helminth infections, and the burden of disease are enormous in sub-saharan africa. co-infections aggravate the clinical outcome, but are common due to an overlap of endemic areas. a cross-sectional survey was conducted to assess prevalence, intensity of infection and association between malaria and soil-transmitted helminth infections in a typical periurban community in kwara state. fresh blood and faecal samples were examined using thick blood film and ... | 2017 | 28442321 |