| the pattern of parasitic infection in villages of lagos state, nigeria. | | 1979 | 396698 |
| antibodies to human immunodeficiency virus (htlv-iii/lav) in people from lagos and cross river states of nigeria. | using enzyme-linked immunosorbent assay (elisa) and confirmatory immunoprecipitation tests, sera from 640 nigerians from lagos and cross river states were examined for antibodies against hiv. these comprised 570 blood donors and their family members, 56 patients with various haematological conditions and 14 patients with acute plasmodium falciparum infection. none of the sera was positive for htlv-iii/lav antibodies by immunoprecipitation, although 12 (1.9%) sera were positive by elisa. | 1988 | 3124480 |
| the parasitic diseases of school children in lagos state, nigeria. | a survey of 5,595 primary school children in lagos state showed that most of the children were over-loaded with parasitic infestations which included malaria (37.7%), schistosomiasis (13.4%). ascariasis (74.2%), trichuriasis (75.8%), hookworm (29.5%) and tungiasis (49.5%). multiple infections were observed with about 16.2% harbouring all the causative organisms of the parasitic diseases enumerated above. the high prevalence of parasitic infestations among these children is an index of the commun ... | 1981 | 6111920 |
| interaction between acute diarrhoea and falciparum malaria in nigerian children. | although both malaria and diarrhoea are major public health problems in developing countries, and separately each has been the subject of intense research, few studies have investigated the interaction between these two conditions. the interaction between diarrhoea and malaria among children aged 4 months to 12 years in two tertiary health-care facilities, university college hospital, ibadan, and lagos university teaching hospital, lagos, nigeria was studied. in ibadan, the prevalence of diarrho ... | 1996 | 9203790 |
| serum ferritin and other haematological measurements in apparently healthy adults with malaria parasitaemia in lagos, nigeria. | we studied 300 apparently healthy residents of lagos aged 16-57 years. their mean ferritin levels were 99.6 +/- 50.5 microg/l (men aged 20-57) and 66.5 +/- 44 microg/l (women aged 20-53) in aparasitaemic individuals. in parasitaemic subjects, mean ferritin levels were 133.1 +/- 48.3 microg/l (men aged 20-56) and 114.8 +/- 51.1 microg/l (women aged 16-50). mean haematocrit values for aparasitaemic males were 45.7 +/- 5.6% and 37.9 +/- 5% for females, while mean haemoglobin levels were 153.2 +/- 1 ... | 2000 | 10995101 |
| dynamics of the malaria-vector populations in coastal lagos, south-western nigeria. | an entomological study was carried out in coastal lagos, south-western nigeria, to explore the role of anopheles gambiae s.l. and an. moucheti in the transmission of plasmodium falciparum in this holo-endemic area. mosquitoes were caught, on human bait at night and by pyrethrum-spray catches during the day, twice a month throughout 2000. of the 1812 anopheles mosquitoes collected, an. gambiae s.l., the predominant vector species, represented 78.7% while the other 21.3% were an. moucheti. the res ... | 2002 | 11989536 |
| malarone treatment failure and in vitro confirmation of resistance of plasmodium falciparum isolate from lagos, nigeria. | we report the first in vitro and genetic confirmation of malarone (glaxosmithkline; atovaquone and proguanil hydrochloride) resistance in plasmodium falciparum acquired in africa. on presenting with malaria two weeks after returning from a 4-week visit to lagos, nigeria without prophylaxis, a male patient was given a standard 3-day treatment course of malarone. twenty-eight days later the parasitaemia recrudesced. parasites were cultured from the blood and the isolate (ngatv01) was shown to be r ... | 2002 | 12057021 |
| congenital malaria among inborn babies at a tertiary centre in lagos, nigeria. | congenital malaria is increasingly reported among babies born to mothers continually residing in endemic areas. given the high morbidity and mortality associated with malaria it is pertinent to determine its current status among newborns in lagos, nigeria. the aim was to determine the incidence of congenital malaria in newborn babies delivered at the lagos university teaching hospital and also to determine the frequency of parasitaemia in their mothers and placentae. a cross-sectional study of m ... | 2006 | 15927946 |
| impact of urbanisation on bionomics and distribution of malaria vectors in lagos, southwestern nigeria. | the patterns of annual, rainfall as well as average daily temperature have not changed drastically in the study area since 1960 when detailed baseline entomological surveys were carried out. however, the increase in human population from 1.2 to 10 million has resulted in both expansion of land and tremendous ecological and environmental change. this has led to drastic changes in vectors' densities as well as species' composition while the preferred larval habitat of malaria vectors has shifted t ... | 2006 | 17175702 |
| salmonellosis in lagos, nigeria: incidence of plasmodium falciparum-associated co-infection, patterns of antimicrobial resistance, and emergence of reduced susceptibility to fluoroquinolones. | the present study was undertaken to examine the status of antimicrobial resistance in salmonella-associated diseases, by verifying possible emergence of reduced susceptibility to fluoroquinolones in salmonella isolates and determining the incidence of plasmodium falciparum-associated co-infection with salmonella serotypes. antimicrobial resistance in clinical isolates of salmonellae was examined for a 12-month period. four hundred and forty-one patients comprising two groups were recruited. grou ... | 2007 | 18330069 |
| clinical presentation of congenital malaria at the lagos university teaching hospital. | congenital malaria has been increasingly documented in endemic regions. it is important to recognize those clinical features that are due to congenital malaria, which if undetected, might worsen the morbidity of the newborn. the aim of this study was to document the clinical presentation of neonates with congenital malaria born at the lagos university teaching hospital and followed up for 28 days. | 2010 | 20499743 |
| knowledge, attitude, perception of malaria and evaluation of malaria parasitaemia among pregnant women attending antenatal care clinic in metropolitan lagos, nigeria. | little information exists on the compliance of pregnant women to malaria management in malaria endemic countries. this study was designed to access knowledge, attitude, perception and home management of malaria among consenting pregnant women attending antenatal care (anc) clinic. | 2011 | 21406732 |
| plasmodium falciparum merozoite surface protein-1 polymorphisms among asymptomatic sickle cell anemia patients in nigeria. | asymptomatic malaria (asm) has been implicated in the development of hemolytic crisis in infected sickle cell anemia (sca) patients worldwide. this study surveyed steady state sca nigerian patients for asm to investigate the influence of malaria prevention behaviors and age on parasitaemia and multiplicity of infection (moi). a total of 78 steady sca patients aged 5 - 27 years on routine care at three health facilities in lagos were investigated for asm by light microscopy and pcr with a multipl ... | 2016 | 26853290 |
| assessment of markers of antimalarial drug resistance in plasmodium falciparum isolates from pregnant women in lagos, nigeria. | the use of antimalarial drugs for prevention and treatment is a major strategy in the prevention of malaria in pregnancy. although sulphadoxine-pyrimethamine (sp) is currently recommended for intermittent preventive treatment of malaria during pregnancy in nigeria, previously used drugs for prophylaxis such as chloroquine (cq) and pyrimethamine are accessible as they are purchased over the counter. this study describes the markers of absence or presence of resistance to quinoline (pfcrt and pfmd ... | 2016 | 26808627 |
| carriage of mutant dihydrofolate reductase and dihydropteroate synthase genes among plasmodium falciparum isolates recovered from pregnant women with asymptomatic infection in lagos, nigeria. | to assess n51i, c59r and s108n polymorphisms of dihydrofolate reductase (dhfr) and a437g and k540e of dihydropteroate synthase (dhps) genes of p. falciparum isolates recovered from pregnant women with asymptomatic malaria in a coastal setting in nigeria. | 2015 | 26202938 |
| persistence of chloroquine-resistant haplotypes of plasmodium falciparum in children with uncomplicated malaria in lagos, nigeria, four years after change of chloroquine as first-line antimalarial medicine. | in nigeria, despite the change in national malaria drug policy to artemisinin combination therapy (act) in 2005 due to widespread chloroquine resistance, chloroquine (cq) is still widely used in the treatment of malaria because it is cheap, affordable and accessible. the use of act for the management of uncomplicated malaria is currently being promoted. the employment of genetic markers to track circulating chloroquine-resistant parasites are useful in elucidating likely poor efficacy of chloroq ... | 2015 | 25928117 |