| [surveillance of the in vivo sensitivity of plasmodium falciparum to antimalarial agents: the results of initial tests of the oceac malaria network]. | the malaria control division of the organization for endemic disease control in central africa (oceac) has developed a standardized method to measure the in vivo sensitivity of plasmodium falciparum to antimalarial drugs. between may 1996 and february 1997, a first series of tests using this method was carried out to determine the sensitivity of plasmodium falciparum to chloroquine and amodiaquine in infected school children in four capital cities: yaoundé, brazzaville, malabo, and libreville. a ... | 1997 | 9612776 |
| surveillance of in vivo resistance of plasmodium falciparum to antimalarial drugs from 1992 to 1999 in malabo (equatorial guinea). | from 1992-1999, we have assessed the therapeutic efficacy of three malaria treatment regimens (chloroquine 25 mg/kg over three days, pyrimethamine/sulfadoxine 1.25/25 mg/kg in one dose, and quinine 25-30 mg/kg daily in three oral doses over a four-, five-, or seven-day period) in 1,189 children under age 10 at malabo regional hospital in equatorial guinea. of those children, 958 were followed up clinically and parasitologically for 14 days. with chloroquine, the failure rate varied from 55% in 1 ... | 2003 | 12812353 |