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decreased sensitivity to chloroquine and quinine of some plasmodium falciparum strains from senegal in september 1984.the in vitro sensitivity of 135 plasmodium falciparum isolates collected in the areas of thies and kaolack, senegal, were studied in september 1984, by means of the 48 hr microtest with 3h-hypoxanthine incorporation. results are available in 110 of 135 cases studied (81%). the isolates collected around kaolack were found on average less sensitive to chloroquine than those from thies (mean ec50 28 and 17 nmol/l of medium, respectively, p less than 0.05) and in 1 isolate a high degree of resistanc ...19863524287
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