| resistance of plasmodium falciparum to antimalarial drugs in a highly endemic area of southern viet nam: a study in vivo and in vitro. | to assess the antimalarial sensitivity of plasmodium falciparum in vivo and in vitro in a highly endemic area of southern viet nam, a field study was conducted (in 1999) at a rubber plantation in binh phuoc province north of ho chi minh city. fifty patients were treated with either artesunate (4 mg/kg on day 0, then 2 mg/kg on day 1 to 4) or mefloquine (10 mg/kg at 0 h, then 5 mg/kg at 6 h), and their progress was followed for 28 days under standard who protocols. blood spots were taken at basel ... | 2001 | 11491008 |
| risk factors for malaria infection among ethnic minorities in binh phuoc, vietnam. | a cross-sectional study was undertaken to identify the prevalence of malaria infection, behavioral patterns of inhabitants and risk factors for malaria infection in a minority village in an area endemic for malaria in vietnam. the target population were all the inhabitants of a village in binh phuoc province, vietnam. interviews using a structured questionnaire and blood examination for malaria infection were conducted in house-to-house visits. relationships between malaria infection and variabl ... | 2009 | 19323029 |
| monitoring for plasmodium falciparum drug resistance to artemisinin and artesunate in binh phuoc province, vietnam: 1998-2009. | artemisinin derivatives have been used for malaria treatment in vietnam since 1989. reported malaria cases have decreased from 1,672,000 with 4,650 deaths in 1991, to 91,635 with 43 deaths in 2006. current national guidelines recommend artemisinin-based combination therapy (act), although artesunate is still available as monotherapy through the private sector. recent reports suggest that effectiveness of act and artesunate monotherapy has declined in western cambodia. this study examined plasmod ... | 2010 | 20573274 |
| polymorphism of plasmodium falciparum na(+)/h(+) exchanger is indicative of a low in vitro quinine susceptibility in isolates from viet nam. | the plasmodium falciparum na+/h+ exchanger (pfnhe1, gene pf13_0019) has recently been proposed to influence quinine (qn) susceptibility. however, its contribution to qn resistance seems to vary geographically depending on the genetic background of the parasites. here, the role of this gene was investigated in in vitro qn susceptibility of isolates from viet nam. | 2011 | 21669011 |