| plasmodium falciparum: sensitivity in vivo to chloroquine, pyrimethamine/sulfadoxine and mefloquine in western myanmar. | in rakhine state, on the western border of myanmar, the efficacy of chloroquine (cq) and pyrimethamine/ sulfadoxine (ps), the current treatments for uncomplicated plasmodium falciparum malaria in this area, was evaluated in an open comparative study of 289 patients, stratified prospectively into 3 age groups. chloroquine treatment was associated with more rapid clinical recovery (p = 0.03), but the overall cure rates were worse than for ps treatment; failure to clear parasitaemia or recrudescenc ... | 1997 | 9373658 |
| efficacy and effectiveness of dihydroartemisinin-piperaquine versus artesunate-mefloquine in falciparum malaria: an open-label randomised comparison. | artemisinin-based combinations are judged the best treatments for multidrug-resistant plasmodium falciparum malaria. artesunate-mefloquine is widely recommended in southeast asia, but its high cost and tolerability profile remain obstacles to widespread deployment. to assess whether dihydroartemisinin-piperaquine is a suitable alternative to artesunate-mefloquine, we compared the safety, tolerability, efficacy, and effectiveness of the two regimens for the treatment of uncomplicated falciparum i ... | 2006 | 16798391 |
| effectiveness of five artemisinin combination regimens with or without primaquine in uncomplicated falciparum malaria: an open-label randomised trial. | artemisinin-combination therapy (act) is recommended as first-line treatment of falciparum malaria throughout the world, and fixed-dose combinations are preferred by who; whether a single gametocytocidal dose of primaquine should be added is unknown. we aimed to compare effectiveness of four fixed-dose acts and a loose tablet combination of artesunate and mefloquine, and assess the addition of a single gametocytocidal dose of primaquine. | 2010 | 20832366 |
| routine parallel diagnosis of malaria using microscopy and the malaria rapid diagnostic test sd 05fk60: the experience of médecins sans frontières in myanmar. | malaria rapid diagnostic tests (rdts) are commonly used in médecins sans frontières (msf) programmes to detect acute malaria infection. programmes in regions with both plasmodium falciparum and non-falciparum malaria (i.e. plasmodium ovale, plasmodium malariae and plasmodium vivax) use a three-band p. falciparum/pan test such as the sd bioline malaria ag p.f/pan 05fk60 (standard diagnostics, kyonggi, republic of korea), hereafter referred to as sd 05fk60, as used by the msf-holland clinics in ra ... | 2013 | 23692957 |