| chloroquine-resistant malaria in burma. | two field trials to detect chloroquine-resistant malaria were conducted according to who recommendations in a malaria free area near rangoon. peripheral blood smears were examined for asexual forms of p. falciparum on day one through to day seven, on day 14, 21, and 28 after a standard dose of 1500 mg. of chloroquine base. haskins test to detect chloroquine in urine was done on all cases and plasma chloroquine levels were measured in some. out of 105 patients tested ri resistance was detected in ... | 1975 | 128638 |
| in vitro sensitivity of plasmodium falciparum isolates from burma to chloroquine quinine and mefloquine. | the in vitro sensitivity of 26 isolates of plasmodium falciparum from rangoon and tharrawaddy areas in burma were studied on chloroquine, mefloquine and quinine. the results indicated that the parasites were highly resistant to chloroquine but sensitive to mefloquine and quinine. the existence of correlation of sensitivity to mefloquine and quinine was detected and discussed. no correlation between the parasite sensitivity to chloroquine and mefloquine and or chloroquine and quinine was detected ... | 1985 | 2937157 |
| isoenzyme characterization of chloroquine-resistant isolates of plasmodium falciparum from burma. | sixty isolates of plasmodium falciparum collected from hospital in-patients in rangoon and out-patients from villages near rangoon were tested in vitro for chloroquine sensitivity and then cultured to carry out starch gel electrophoresis of the following parasite enzyme: glucose phosphate isomerase (gpi) (ec.5.3.1.9.), nadp-dependent glutamate dehydrogenase (gdh) ec.1.4.1.4), lactate dehydrogenase (ldh) (ec.1.1.1.27) and 6-phosphogluconate dehydrogenase (6pgd) (e.c.1.1.1.44). variations were obs ... | 1984 | 6091301 |
| validation of g6pd point-of-care tests among healthy volunteers in yangon, myanmar. | primaquine and other 8-amnoquinoline based anti-malarials can cause haemolysis in subjects with glucose-6-phosphate dehydrogenase (g6pd) deficiency. correct diagnosis of g6pd status in patients is crucial for safe treatment of both relapsing stages of plasmodium vivax and transmitting forms of plasmodium falciparum. lack of suitable point-of-care tests has hampered a much needed wide use of primaquine for malaria elimination. in this study we have assessed the performances of two qualitative tes ... | 2016 | 27035821 |