| changing response of plasmodium falciparum to chloroquine in west bengal during 1980-1988. | a total of 314 cases of plasmodium falciparum malaria studied during 1980-88 in nine times monitoring revealed three riii foci i.e. two in jalpaiguri and one in purulia districts. the studies showed a parasite clearance of 40 per cent and 32 per cent of p. falciparum cases within seventh day in purulia and jalpaiguri districts respectively, with a dosage of 25 mg per kg body weight, spread over three days in divided doses. increase in transmission potential and prolonged drug pressure with singl ... | 1991 | 1940214 |
| efficacy of sulfalene and pyrimethamine combination drugs alone and with quinine in treatment of p. falciparum cases in chloroquine resistant areas of north east india. | studies were carried out in some areas of assam, nagaland, west bengal and mizoram where chloroquine resistant strains of plasmodium falciparum were present during 1983 and 1984, to see the efficacy of treatment of p. falciparum cases with slp alone or with quinine sulphate. the findings have indicated that slp in the dosage of sulfalene (1000 mg) + pyrimethamine (50 mg) is suitable for treatment of p. falciparum cases not responding to chloroquine therapy in n.e. india. treatment with sulfalene ... | 1990 | 2098422 |
| distribution of plasmodium falciparum in west bengal. | | 1980 | 7001693 |
| the sickle cell trait in the santhals of ajodhya hills of purulia district, west bengal. | | 1981 | 7034322 |
| recent epidemiological status of malaria in calcutta municipal corporation area, west bengal. | in calcutta, plasmodium falciparum cases and death due to malaria show remarkably increasing trend since 1990. the incidence of p. falciparum malaria has increased more than eleven folds in 1996 in comparison to 1990, with 0, 0, 0, 3, 7, 52 and 17 deaths in 1990, 1991, 1992, 1993, 1994, 1995 and 1996 respectively. situation is more serious than what it is projected in official records as annual blood examination rate (aber) in calcutta municipal area is poor, varying from 1.5 to 3.9 in 1993 and ... | 1997 | 9699422 |
| estimating parasite density in patients suffering from falciparum malaria in an endemic area in kolkata. | parasite density of one hundred patients suffering from falciparum malaria in an endemic area in kolkata was determined using three different methods. in the first of these, parasite density per microlitre of blood in a patient was determined using parasite count adjusted by average wbc count (i.e. 8000/microliter) observed in microscopic fields of the thick film. in the remaining two methods, only raw (i.e. unadjusted) parasite counts in microscopic fields of the same slide were used. a statist ... | 2000 | 11820090 |
| malariogenic situations in areas of aiodhya hills of the district purulia west bengal and its present status. | | 2001 | 11917319 |
| monitoring the chloroquine sensitivity of plasmodium vivax from calcutta and orissa, india. | chloroquine-resistant plasmodium vivax malaria was first reported in india in 1995. this report led to the round-the-year monitoring, in calcutta (west bengal) and mayurbhanj district (northern orissa), of the in-vivo sensitivity of local p. vivax to chloroquine (cq). between january 1998 and december 2001, 800 cases with microscopically confirmed p. vivax malaria were enrolled in the study. each was given cq in the regimen recommended both by the government of india and the world health organiz ... | 2003 | 12803853 |
| genetic structure of plasmodium falciparum field isolates in eastern and north-eastern india. | molecular techniques have facilitated the studies on genetic diversity of plasmodium species particularly from field isolates collected directly from patients. the msp-1 and msp-2 are highly polymorphic markers and the large allelic polymorphism has been reported in the block 2 of the msp-1 gene and the central repetitive domain (block3) of the msp-2 gene. families differing in nucleotide sequences and in number of repetitive sequences (length variation) were used for genotyping purposes. as lim ... | 2007 | 17517129 |
| age composition of incriminated malaria vector in a rural foothills in west bengal, india. | two 1 yr surveys carried out at a gap of 10 yr revealed nine anopheline species from malaria endemic foothills area of ayodhya - baghmindi range of west bengal, india, with 8.4 per cent populations of anopheles culicifacies. an. culicifacies was incriminated as vector of plasmodium falciparum with sporozoite rate of 1.23 per cent. studies on age composition indicated that proportion parous and daily survival rate of an. culicifacies were assessed to be 0.50 and 0.84 respectively. the survival ra ... | 2008 | 18765881 |
| increasing incidence of malaria in kurseong, darjeeling district, west bengal, india, 2000-2004. | in kurseong, darjeeling district, india, malaria caused concern but insufficient information was available. we analysed surveillance data to estimate the burden of malaria and to examine trends. confirmed malaria reports were reviewed and climatic records were collected. the annual parasite incidence (api; number of cases/population) and the annual blood examination rate (aber; number of slides examined/population) were calculated to assess case detection activities, and the slide positivity rat ... | 2009 | 18786685 |
| risk factors for malaria deaths in jalpaiguri district, west bengal, india: evidence for further action. | in 2006, a cluster of malaria deaths in the highly endemic jalpaiguri district, west bengal, india, led to assignment of additional resources. malaria deaths decreased, but continued to occur. a study was conducted to identify the risk factors for residual malaria deaths. | 2009 | 19527528 |
| the risk of malaria in travelers to india. | several countries have reported a decline in malaria cases imported by travelers returning from india. | 2009 | 19538581 |
| a malaria outbreak in naxalbari, darjeeling district, west bengal, india, 2005: weaknesses in disease control, important risk factors. | an outbreak of malaria in naxalbari, west bengal, india, in 2005 was investigated to understand determinants and propose control measures. malaria cases were slide-confirmed. methods included calculation of annual blood examination rates (aber, number of slides examined/population), collection of water specimens from potential vector-breeding sites, sorting of villages in categories depending on the number of abandoned wells within two kilometers radius and review of the ddt spray coverage. case ... | 2009 | 20003288 |
| efficacy of chloroquine and sulphadoxine-pyrimethamine either alone or in combination before introduction of act as first-line therapy in uncomplicated plasmodium falciparum malaria in jalpaiguri district, west bengal, india. | objective  in india, till recently, chloroquine was used as first-line therapy in areas with chloroquine sensitive plasmodium falciparum malaria cases. the national vector borne disease control programme (nvbdcp) has introduced artemisinin combination therapy (act) as first-line option to treat all p. falciparum cases in the country. this study was carried out to ascertain the efficacy of chloroquine and sulphadoxine-pyrimethamine, either alone or in combination, before the launch of act by nvbd ... | 2011 | 21564429 |
| polymorphisms in pfcrt and pfmdr-1 genes after five years withdrawal of chloroquine for the treatment of plasmodium falciparum malaria in west bengal, india. | the emergence of resistant power against different antimalarial agents particularly by plasmodium falciparum is a challenge to combat malaria. regular monitoring is essential not only to determine the efficacy and development of resistance by the parasite but also to detect early sign of regaining sensitivity to any anti-malarial agent that has been withdrawn for a long period. studies on molecular markers associated with antimalarial drug resistance of prevailing plasmodium population play an i ... | 2016 | 27448953 |
| genetic diversity and multiplicity of infection of plasmodium falciparum isolates from kolkata, west bengal, india. | the study of genetic diversity of plasmodium falciparum is necessary to understand the distribution and dynamics of parasite populations. the genetic diversity of p. falciparum merozoite surface protein-1 and 2 has been extensively studied from different parts of world. however, limited data are available from india. this study was aimed to determine the genetic diversity and multiplicity of infection (moi) of p. falciparum population in kolkata, west bengal, india. a total of 80day-zero blood s ... | 2016 | 27259367 |
| malaria treatment failure with novel mutation in the plasmodium falciparum dihydrofolate reductase (pfdhfr) gene in kolkata, west bengal, india. | the aim of this work was to define the cause of sulfadoxine/pyrimethamine (sp) treatment failure in plasmodium falciparum infections in a malaria-endemic zone of india. samples were collected from 176 patients in kolkata from november 2008 to july 2009. in vitro susceptibility testing was performed on all isolates. parasite dna was extracted, and pcr and restriction fragment length polymorphism (rflp) analysis of different codons of the dhfr gene (16, 51, 59, 108 and 164) and dhps gene (436, 437 ... | 2013 | 23428313 |
| high prevalence of asymptomatic malaria in a tribal population in eastern india. | asymptomatic infection by plasmodium falciparum is an important obstacle to eliminating malaria. asymptomatic carriers do not seek treatment for infection, and therefore they become a reservoir for the parasite. for this reason, these carriers pose a real public health risk. the systematic identification and treatment of asymptomatic infections should reduce the parasite reservoir. a large reduction in this pool will lower the chance of transmission of the disease. in this study, we screened a t ... | 2013 | 23426929 |
| incidence, management, and reporting of severe and fatal plasmodium falciparum malaria in secondary and tertiary health facilities of alipurduar, india in 2009. | the proportion of malaria cases that are complicated and fatal are not well described in india. alipurduar sub-division of jalpaiguri district in west bengal is highly endemic for malaria. we constructed a retrospective cohort of severe malaria patients admitted in the secondary and tertiary care facilities in alipurduar to determine the incidence, assess the management, and evaluate the reporting of severe and fatal malaria. | 2012 | 23135010 |
| novel quadruple mutations in dihydropteroate synthase genes of plasmodium falciparum in west bengal, india. | to evaluate the anti-folate (sulphadoxine)-resistant pattern in kolkata, one of the malaria endemic zones of eastern india. | 2012 | 22909027 |
| progressive increase in point mutations associates chloroquine resistance: even after withdrawal of chloroquine use in india. | chloroquine (cq) is highly effective against p. vivax, due to the rapid spread of cq resistance in p. falciparum parasites; it is no longer the drug of choice against p. falciparum. this study elucidates the scenario of chloroquine efficacy at times that coincided with a new drug policy and especially assessed the chloroquine resistant molecular markers after withdrawal of chloroquine in kolkata and purulia, two malaria endemic zones of west bengal, india. in vitro cq susceptibility was tested i ... | 2017 | 28692943 |