| habitat partitioning of malaria vectors in nchelenge district, zambia. | nchelenge district in luapula province, northern zambia, experiences holoendemic malaria despite implementation of vector control programs. the major anopheles vectors that contribute to plasmodium falciparum transmission in this area had not previously been well defined. three collections performed during the 2012 wet and dry seasons and the 2013 wet season revealed anopheles funestus sensu stricto and anopheles gambiae sensu stricto as the main vectors, where 80-85% of each collection was comp ... | 2016 | 27001755 |
| plasmodium falciparum parasite infection prevalence from a household survey in zambia using microscopy and a rapid diagnostic test: implications for monitoring and evaluation. | this paper presents estimates of p. falciparum infection prevalence in children under 5 years old in the context of a population-based household survey in luangwa district (lusaka province), zambia, an area where greater than 75% of households possess at least one insecticide-treated mosquito net (itn). the sensitivity and specificity of an hrp-2 rapid diagnostic test (rdt) (ict malaria pf((r))) compared to microscopy, as well as factors associated with discordant diagnostic results are also pre ... | 2009 | 19682968 |
| a comparison of the sensitivity of plasmodium falciparum malaria to chloroquine in two areas of isoka district--zambia. | | 1988 | 3075157 |
| elisa method for detecting plasmodium falciparum circumsporozoite antibody. | an enzyme-linked immunosorbent assay (elisa) for circulating igg mouse antibody to plasmodium falciparum circumsporozoite (cs) protein was modified for use with human sera collected in an area of northern zambia that was endemic for malaria and from individuals never exposed to malaria. optimum sensitivity was achieved using immulon 2 microtitration plates, boiled casein-tween 20 blocking buffer, and by adding a solution of boiled casein (4 micrograms/ml) to the capture antigen diluent. the resu ... | 1989 | 2692869 |
| high burden of malaria infection in pregnant women in a rural district of zambia: a cross-sectional study. | malaria continues to be a major health problem in low-income countries. consequently, malaria control remains a public health priority in endemic countries such as zambia. pregnant women and children under 5 years of age are among groups at high risk of malaria infection. malaria infection is associated with adverse birth outcomes that affect the mother, foetus, and infant. infection with hiv has been shown to increase the risk of malaria infection in pregnancy. the prevalence and the predictors ... | 2015 | 26423819 |
| beyond the entomological inoculation rate: characterizing multiple blood feeding behavior and plasmodium falciparum multiplicity of infection in anopheles mosquitoes in northern zambia. | a commonly used measure of malaria transmission intensity is the entomological inoculation rate (eir), defined as the product of the human biting rate (hbr) and sporozoite infection rate (sir). the eir excludes molecular parameters that may influence vector control and surveillance strategies. the purpose of this study was to investigate anopheles multiple blood feeding behavior (mbf) and plasmodium falciparum multiplicity of infection (moi) within the mosquito host in nchelenge district, northe ... | 2017 | 28122597 |
| high prevalence of dhfr and dhps molecular markers in plasmodium falciparum in pregnant women of nchelenge district, northern zambia. | sulphadoxine-pyrimethamine (sp) is the recommended drug for intermittent preventive treatment in pregnancy (iptp) in most african countries, including zambia. however, malaria is still one of the leading causes of morbidity and mortality in pregnant women despite reports of greater than 50% of women taking at least two doses of sp in iptp. studies have shown that resistance to sp is associated with mutations in the dhfr and dhps gene of plasmodium falciparum. this study examined the prevalence o ... | 2015 | 25943379 |
| defining the malaria burden in nchelenge district, northern zambia using the world health organization malaria indicators survey. | malaria is considered as one of the major public health problems and among the diseases of poverty. in areas of stable and relatively high transmission, pregnant women and their newborn babies are among the higher risk groups. a multicentre trial on the safety and efficacy of several formulations of artemisinin-based combination therapy (act) during pregnancy is currently on-going in four african countries, including zambia, whose study site is in nchelenge district. as the study outcomes may be ... | 2014 | 24902708 |