Publications

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chloroquine resistance of plasmodium falciparum malaria in ethiopia and eritrea.we report on the first 2 years of operation of a new strategy for treatment for p. falciparum malaria patients who were not cured by a standard course of chloroquine. any such patient who returned to a malaria treatment and detection post within 2 weeks was treated daily under supervision with chloroquine. patients whose parasitaemia had not decreased below 25% of the initial level by day 3 or cleared completely by day 7 were given sulphadoxine/pyrimethamine (fansidar). of 39824 patients treated ...19968980594
magnitude of malaria admissions and deaths at hospitals and health centers in oromia, ethiopia.health facility records are important sources of malaria data, not only to describe the disease patterns and trends, but also useful for planning malaria control and evaluating the impact of health interventions. the aim of this study was to assess the burden of malaria admissions and deaths on the services of hospitals and health centers in oromia, over a period of five years, 1995-2000. a retrospective record review of data routinely collected on malaria admissions and deaths was conducted at ...200416122115
molecular surveillance of mutations in dihydrofolate reductase and dihydropteroate synthase genes of plasmodium falciparum in ethiopia.point mutations in the genes for dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) of plasmodium falciparum isolates are associated with sulfadoxine/pyrimethamine (sp) treatment failure, respectively. this study was conducted to assess the prevalence of sp resistance in p. falciparum isolates collected at the jimma health center in southwestern ethiopia. in this study, the genetic profile of p. falciparum isolates with respect to dhfr and dhps genes was assessed in 124 individua ...200516354825
malaria and water resource development: the case of gilgel-gibe hydroelectric dam in ethiopia.ethiopia plans to increase its electricity power supply by five-fold over the next five years to fulfill the needs of its people and support the economic growth based on large hydropower dams. building large dams for hydropower generation may increase the transmission of malaria since they transform ecosystems and create new vector breeding habitats. the aim of this study was to assess the effects of gilgel-gibe hydroelectric dam in ethiopia on malaria transmission and changing levels of prevale ...200919178727
evaluation of the performance of carestart malaria pf/pv combo rapid diagnostic test for the diagnosis of malaria in jimma, southwestern ethiopia.to evaluate the diagnostic performance of carestart malaria pf/pv combo test relative to microscopy, for the diagnosis of falciparum and vivax malaria in ethiopia.201020005196
different mutation patterns of plasmodium falciparum among patients in jimma university hospital, ethiopia.the emergence of drug resistance is a major problem in malaria control. combination of molecular genotyping and characterization of mutations or single nucleotide polymorphisms (snps) correlated with drug resistance can provide information for subsequent surveillance of existing and developing drug resistance patterns. the introduction of artemether/lumefantrine (al) as first-line treatment, never used before in ethiopia, allowed the collection of baseline data of molecular polymorphisms before ...201020691106
performance of three multi-species rapid diagnostic tests for diagnosis of plasmodium falciparum and plasmodium vivax malaria in oromia regional state, ethiopia.malaria transmission in ethiopia is unstable and variable, caused by both plasmodium falciparum and plasmodium vivax. the federal ministry of health (fmoh) is scaling up parasitological diagnosis of malaria at all levels of the health system; at peripheral health facilities this will be through use of rapid diagnostic tests (rdts). the present study compared three rdt products to provide the fmoh with evidence to guide appropriate product selection.201020979601
school-based surveys of malaria in oromia regional state, ethiopia: a rapid survey method for malaria in low transmission settings.in ethiopia, malaria transmission is seasonal and unstable, with both plasmodium falciparum and plasmodium vivax endemic. such spatial and temporal clustering of malaria only serves to underscore the importance of regularly collecting up-to-date malaria surveillance data to inform decision-making in malaria control. cross-sectional school-based malaria surveys were conducted across oromia regional state to generate up-to-date data for planning malaria control interventions, as well as monitoring ...201121288368
validity and reliability of rdt for diagnosis of malaria among febrile children in jimma town: southwest ethiopia.malaria shows variations in its epidemiologic pattern in relation to the local situation. rapid diagnostic tests (rdts) have the potential to provide an accurate diagnosis and to determine the prevalence of malaria in ureas.201121796913
malaria, oromia regional state, ethiopia, 2001-2006.to the editor: in ethiopia, malaria is unstable and commonly occurs as intraannual and interannual epidemics. transmission is associated with altitude, temperature, and rainfall, generally peaking twice a year, after the 2 rainy seasons (march-may and july-september) (1). cases are caused by plasmodium falciparum and p. vivax. anopheles arabiensis mosquitoes are the main vector for both species. although malaria is the most common communicable disease in ethiopia (2), few longitudinal case data ...201121762615
urban malaria and associated risk factors in jimma town, south-west ethiopia.malaria kills millions around the world. until recently it was believed to be a disease of rural areas, since the anopheles mosquito, which transmits plasmodium species breeds in rural areas. urban malaria is emerging as a potential, but "avertable" crisis, in africa. in view of the rapidly growing number of small and medium-sized towns in ethiopia there is a pressing need to improve the understanding of the epidemiology of malaria. therefore, the aim of this study was to determine malaria preva ...201121699741
geostatistical modeling of malaria endemicity using serological indicators of exposure collected through school surveys.ethiopia has a diverse ecology and geography resulting in spatial and temporal variation in malaria transmission. evidence-based strategies are thus needed to monitor transmission intensity and target interventions. a purposive selection of dried blood spots collected during cross-sectional school-based surveys in oromia regional state, ethiopia, were tested for presence of antibodies against plasmodium falciparum and p. vivax antigens. spatially explicit binomial models of seroprevalence were c ...201525962770
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