| parasitological, clinical and haematological response of children with plasmodium falciparum to 4-aminoquinolines and to pyrimethamine-sulfadoxine with quinine in western kenya. | children with plasmodium falciparum infections in western province, kenya, were studied in 1987 for their parasitological, clinical and haematological response to chloroquine, to amodiaquine and to pyrimethamine-sulfadoxine plus quinine. ninety-eight children under 5 years of age were treated in 1 of 2 hospitals. of the 56 patients treated with chloroquine base 25 mg/kg, 91% had resistant infections, with 36% having no significant decrease in parasitaemia (riii resistance); however, 69% responde ... | 1992 | 1496699 |
| sensitivity of falciparum malaria to chloroquine and amodiaquine in four districts of western kenya (1985-1987). | in-vivo and in-vitro studies to determine the sensitivity of plasmodium falciparum malaria to chloroquine and amodiaquine were conducted in 4 districts of western kenya over a 2-year-period. patients aged 5-60 years, were treated with chloroquine or amodiaquine base 25 mg/kg over 3 days. recurrence of parasitaemia within 7 days (r1 resistance) or failure to clear parasites (r11 resistance) was observed in 27% of infections in west pokot district, 51% in busia, 45% in bungoma and 19% in rusinga i ... | 1991 | 1765012 |
| sickle cell trait and plasmodium falciparum parasitaemia in pregnancy in western province, kenya. | | 1985 | 4095754 |
| sensitivity of plasmodium falciparum to chloroquine in busia district, kenya. | individuals infected with plasmodium falciparum were randomly divided into two groups; one group was treated with a single dose of 10 mg chloroquine base per kg. body-weight and the other with 25 mg base of chloroquine per kg body-weight given over three days, followed by an observation period of seven days. by day 3 of observation complete parasite clearance had occurred in all the 125 triple dose recipients and 113 of 114 (99.1%) of those who had the single dose. 94.4% of 36 isolates tested in ... | 1982 | 7051452 |
| seasonal density, sporozoite rates and entomological inoculation rates of anopheles gambiae and anopheles funestus in a high-altitude sugarcane growing zone in western kenya. | an entomological study was conducted on vectors of malaria and their relative contribution to plasmodium falciparum transmission in mumias, a high-altitude site and large-scale sugarcane growing zone in kakamega district, western kenya. anopheles gambiae s.l., the predominant vector species, represented 84% (n=2667) of the total anopheles mosquitoes collected with an. funestus comprising only 16%. polymerase chain reaction (pcr) identified all 600 specimens of the an. gambiae complex tested as a ... | 1998 | 9754665 |
| comparison of the parasitologic efficacy of amodiaquine and sulfadoxine-pyrimethamine in the treatment of plasmodium falciparum malaria in the bungoma district of western kenya. | the efficacy of amodiaquine (aq) and sulfadoxine-pyrimethamine (sp) was assessed in 310 symptomatic children from western kenya with uncomplicated plasmodium falciparum malaria. a non-blinded, randomized, 14-day study was performed and parasitologic criteria were used. of 310 patients included, 238 (77%) completed the study: 120 received aq and 118 received sp. in those treated with aq, there were sensitive (s) infections in 107 patients (89.2%, 95% confidence interval [ci] = 82.2, 94.1%), ri re ... | 2004 | 15569779 |
| population dynamics of malaria vectors in western kenya highlands. | studies were carried out at three sites in the highlands of western kenya (iguhu and mbale in kakamega and vihiga districts, respectively, and marani in kisii district) and at one site in the western kenya lowlands (kombewa in kisumu district) to determine the spatial-temporal dynamics of malaria vectors and intensity of malaria transmission from june 2003 to june 2004. at the highland sites, anopheles gambiae giles predominated, constituting >80% of the vector species, whereas an. funestus gile ... | 2006 | 16619599 |
| efficacy and safety of an artesunate/mefloquine combination, (artequin) in the treatment of uncomplicated p. falciparum malaria in kenya. | although artesunate and mefloquine have been used as monotherapies in the treatment of malaria in kenya for a long time, there is insufficient data on the clinical outcome when used as combination therapy in this population. | 2006 | 16866217 |
| literacy and recent history of diarrhoea are predictive of plasmodium falciparum parasitaemia in kenyan adults. | malaria is one of the most serious health problems in kenya. in 2004, the kenya medical research institute and the us army medical research unit--kenya surveyed adults in samburu, malindi, and busia districts to determine socioeconomic risk factors for infection. | 2006 | 17076908 |
| community-wide benefits of targeted indoor residual spray for malaria control in the western kenya highland. | interest in indoor residual spray (irs) has been rekindled in recent years, as it is increasingly considered to be a key component of integrated malaria management. regular spraying of each human dwelling becomes less and less practical as the control area increases. where malaria transmission is concentrated around focal points, however, targeted irs may pose a feasible alternative to mass spraying. here, the impact of targeted irs was assessed in the highlands of western kenya. | 2010 | 20199674 |
| low reliability of home-based diagnosis of malaria in a rural community in western kenya. | home-based management of malaria is promoted as a major strategy for improving prompt delivery of effective malaria treatment in africa. this study aimed to determine the proportion of children who tested positive for malaria with routine light microscopy among those whose mothers had made a home-based diagnosis in a rural community in western kenya. | 2011 | 21330741 |
| assessment of iron status among preschool children (6 to 59 months) with and without malaria in western province, kenya. | iron deficiency is a major public health concern. globally, iron deficiency ranks number 9 and is responsible for about 60% of all anemia cases among preschool children. in africa iron deficiency is 43-52% while in kenya, children under 5 years constitute the largest burden with 69% of them being deficient. there is limited iron deficiency data in kenya. this study determined haemoglobin levels, serum ferritin levels, nutritional status and p.falciparum malaria infection in preschool children. | 2015 | 26405498 |