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secretory iga against enterotoxins in breast-milk.a pool of colostrum from guatemalan mothers (guatemalan colostrum)) obtained 2-4 days post partum inhibited the induced fluid accumulation in rabbit ileal loops when incubated with vibrio cholerae or escherichia coli enterotoxin. there was a linear relationship between the quantity of colostrum used and the protection achieved. pools of guatemalan breast-milk obtained 15-30 days post partum and north american breast-milk had the same effect when tested with e. coli and v. cholerae enterotoxins, ...197673692
the immune response of the mammary gland and its significance for the neonate.the immune response of the mammary gland is dominated by local production of secretory iga antibodies (siga). these milk antibodies, amounting to about 0.5-1 g/day throughout lactation, are directed against food proteins and microorganisms often present in the intestine. this is presumably explained by the enteromammaric link: after antigenic exposure in the peyer's patches of lymphoid cells they home to various exocrine glands, including the mammary gland. similarly, lymphoid cells from the bro ...19846391286
plants used in guatemala for the treatment of gastrointestinal disorders. iv. vibriocidal activity of five american plants used to treat infections. 19938331964
epidemic cholera in guatemala, 1993: transmission of a newly introduced epidemic strain by street vendors.epidemic cholera reached guatemala in july 1991. by mid-1993, guatemala ranked third in the hemisphere in reported cases of cholera. we conducted a case-control study with two age-, sex-, and neighbourhood-matched controls per patient in periurban guatemala city. twenty-six patients hospitalized for cholera and 52 controls were enrolled. seven (47%) of 15 stool cultures obtained after admission yielded toxigenic vibrio cholerae o1. all seven were resistant to furazolidone, sulfisoxazole, and str ...19968620902
nosocomial infection due to vibrio cholerae in two referral hospitals in guatemala.we report nosocomial infection with vibrio cholerae 01, in four seriously ill individuals and one infant in guatemala. nosocomial cholera occurs in developing countries in latin america and should be suspected in hospitalized patients with diarrhea, especially during community outbreaks, in order to institute appropriate diagnostic, therapeutic, and control measures.19968805070
genetic diversity and population structure of vibrio cholerae.multilocus enzyme electrophoresis (mlee) of 397 vibrio cholerae isolates, including 143 serogroup reference strains and 244 strains from mexico and guatemala, identified 279 electrophoretic types (ets) distributed in two major divisions (i and ii). linkage disequilibrium was demonstrated in both divisions and in subdivision ic of division i but not in subdivision ia, which includes 76% of the ets. despite this evidence of relatively frequent recombination, clonal lineages may persist for periods ...19999986816
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