albendazole in the treatment of onchocerciasis: double-blind clinical trial in venezuela. | a double-blind clinical trial was conducted in monagas state, venezuela to assess the tolerance and efficacy of albendazole in the therapy of onchocerca volvulus infection. forty-nine patients (26 treated and 23 controls) received a 10-day course of albendazole (400 mg/day) or a placebo. consistent with the excellent tolerance observed, albendazole did not kill microfilariae. however, analysis of changes in microfilarial densities (mf/mg of skin) over one year showed that albendazole was active ... | 1992 | 1443350 |