| importance of migrants infected with onchocerca volvulus in west african river valleys protected by 14 to 15 years of simulium control. | a study was done to determine the importance of human migration from non-controlled endemic onchocerciasis foci to the river valleys that have been protected for the past 14 to 15 years by the vector control operations of the onchocerciasis control programme in west africa. the aim of the study was to assess the contribution of migrants to the prevalence and intensity of infection in villages from 5 major river valleys and their potential role in causing relapse of transmission once the vector i ... | 1991 | 1654591 |
| a survey of simulium control in africa. | it has become possible to control or even eradicate the simulium fly vectors of onchocerca volvulus, the causative organism of onchocerciasis. there are two vectors in africa-namely, s. damnosum, characteristic of the rivers of west africa, and s. neavei, which breeds on the carapaces of crabs in the streams of east africa. the use of ddt applied to the water at a concentration as low as 0.1 p.p.m. for 30 minutes eliminates the larvae of simulium. such larvicidal methods have eradicated s. neave ... | 1962 | 14015908 |
| identification of variant abc-transporter genes among onchocerca volvulus collected from ivermectin-treated and untreated patients in ghana, west africa. | treatment with ivermectin (ivm) is known to cause a loss of polymorphism at certain loci of the beta-tubulin, gamma-aminobutyric-acid-receptor, glutamate-gated-chloride-channel and atp-binding-cassette (abc) transporter genes of ivm-resistant haemonchus contortus. the genetic variation of four abc-transporter homologues from onchocerca volvulus was therefore investigated, to determine if any change in genetic polymorphism occurs in these genes following repeated treatment with ivm. samples were ... | 2004 | 15228718 |