| hepatitis delta virus genotype iib predominates in an endemic area, okinawa, japan. | hepatitis delta virus (hdv) infection is relatively common in the miyako islands, okinawa, japan, where the infection has been reported to be associated with low pathogenicity. hdv rna extracted from each of 6 patients with hdv-related chronic liver disease living in the islands was amplified by reverse transcription-polymerase chain reaction and examined genetically to determine the hdv genotype. all isolates from the 6 patients were classified as genotype ii by the neighbor-joining method. how ... | 1999 | 10421403 |
| genotype analysis, using pcr with type-specific primers, of hepatitis b virus isolates from patients coinfected with hepatitis delta virus genotype ii from miyako island, japan. | the aims of this study were to determine the hepatitis b virus (hbv) genotypes in hepatitis delta virus (hdv) rna-positive patients and to characterize the hbv nucleotide sequences that may be found on a distant island of japan. | 2003 | 12684550 |
| full genomic analysis of hepatitis delta virus prevalent on miyako island, japan. | the aims of this study were to determine the full-length genome sequences of hepatitis delta virus (hdv) in hdv rna-positive subjects, and to elucidate the molecular specificity of the hdvs that are clustered on a distant island in japan. this study included 3 subjects with chronic hepatitis who were positive for hepatitis b surface (hbs) antigen and hdv rna, and who were admitted to the okinawa prefectural miyako hospital in 1998. the full-length genome sequence of hdv was determined by nested ... | 2005 | 15920349 |
| prevalence and clinical features of hepatitis delta virus infection in the miyako islands, okinawa, japan. | the aims of this study were twofold: (1) to determine the prevalence and clinical features of hepatitis delta virus (hdv) infection among subjects positive for hepatitis b surface antigen (hbsag) living in the miyako islands, okinawa prefecture, japan, and (2) to clarify the relationship between hdv-rna level and severity of hdv-related liver disease. one hundred and ninety-nine hbsag-positive subjects (123 asymptomatic carriers [ascs], 3 patients with acute hepatitis [ah], 50 patients with chro ... | 1998 | 9853558 |
| seroepidemiological study on hepatitis delta virus infection in the irabu islands, okinawa, japan. | a seroepidemiological study was performed to clarify the prevalence of hepatitis delta virus (hdv) infection among the general population in the irabu islands, okinawa, japan. of 2028 healthy people examined who had received their annual health check-up in 1994-95, 195 (9.6%) were positive for hepatitis b surface antigen (hbsag). of these 195 hbsag-positive individuals, 46 (23.6%) showed a positive reaction for antibody to hdv (anti-hdv). the positivity rate of anti-hdv among hbsag-positive subj ... | 1997 | 9195370 |
| seroepidemiological study of hepatitis delta virus infection in okinawa, japan. | a seroepidemiological study on hepatitis delta virus (hdv) infection was conducted in the okinawan islands, the area of japan where hepatitis b virus infection is most prevalent. the subjects of this study included 116 asymptomatic hepatitis b surface antigen (hbsag) carriers, 48 patients with chronic hepatitis (ch), 19 with liver cirrhosis (lc), and 11 with hepatocellular carcinoma (hcc). among the 194 serum samples examined, a total of 10 (5.2%) were anti-hdv seropositive. anti-hdv was detecte ... | 1995 | 7775953 |
| the complete genomic sequence of hepatitis delta virus genotype iib prevalent in okinawa, japan. | the miyako islands, located in the southernmost part of japan, have been reported to be endemic for hepatitis delta virus (hdv). the majority of hdv patients in this area exhibit a relatively mild course of infection that evolves into a quiescent cirrhotic condition. the entire nucleotide sequence of the miyako isolate (l215) of hdv obtained from a cirrhotic patient infected with hdv was determined. this isolate, l215, comprises 1682 nt and encodes 213 aa of the hepatitis delta antigen. phylogen ... | 2003 | 12560580 |
| molecular analysis of hepatitis d virus infection in miyako island, a small japanese island. | the present investigation attempted to determine the exact prevalence of hepatitis d virus (hdv) infection among inhabitants of miyako island (a remote island in the okinawa prefecture) and the molecular characteristics of the hdv genome that was isolated. among the 4728 inhabitants, 375 (7.9%) were hepatitis b surface antigen (hbsag) positive. antibody to hdv (anti-hdv) was present in 32 (8. 5%) of these 375 subjects, and liver function tests were normal in most subjects. the presence of hdv rn ... | 2000 | 10971826 |