| molecular typing and exopolysaccharide biosynthesis of burkholderia cepacia isolates from a portuguese cystic fibrosis center. | this work describes the first epidemiological survey of burkholderia cepacia involved in pulmonary infections among the portuguese population with cystic fibrosis (cf) who attended the major cf treatment center in lisbon at sta. maria hospital from 1995 to the end of 1997. the characterization of the genomic relatedness of the isolates was based on the analysis of their ribopatterns (with ecori) followed by construction of a ribotype-based phylogenetic tree. this study was complemented with macr ... | 2000 | 10747161 |
| exceptionally high representation of burkholderia cepacia among b. cepacia complex isolates recovered from the major portuguese cystic fibrosis center. | burkholderia cepacia, a species found infrequently in cystic fibrosis (cf), was isolated from 85% of patients infected with bacteria of the b. cepacia complex that visited the major portuguese cf center, in lisbon, during 2003 to 2005. a detailed molecular analysis revealed that this was mainly due to two b. cepacia clones. these clones were indistinguishable from two strains isolated from intrinsically contaminated nonsterile saline solutions for nasal application, detected during routine marke ... | 2007 | 17360834 |
| long-term colonization of the cystic fibrosis lung by burkholderia cepacia complex bacteria: epidemiology, clonal variation, and genome-wide expression alterations. | long-term respiratory infections with burkholderia cepacia complex (bcc) bacteria in cystic fibrosis (cf) patients generally lead to a more rapid decline in lung function and, in some cases, to a fatal necrotizing pneumonia known as the "cepacia syndrome." bcc bacteria are ubiquitous in the environment and are recognized as serious opportunistic pathogens that are virtually impossible to eradicate from the cf lung, posing a serious clinical threat. the epidemiological survey of bcc bacteria invo ... | 2011 | 22919578 |
| incidence of burkholderia contaminans at a cystic fibrosis centre with an unusually high representation of burkholderia cepacia during 15 years of epidemiological surveillance. | the burkholderia cepacia complex (bcc) is a heterogeneous group of bacteria comprising around 20 related species. these bacteria are important opportunistic pathogens, especially in cystic fibrosis (cf) patients, and are associated with a worse prognosis and decreased life expectancy. the taxonomic position of 20 bcc isolates retrieved from cf patients receiving care at hospital santa maria (hsm), in lisbon, from 1995 to 2006, was re-examined in the present work. these isolates, formerly classif ... | 2015 | 26002942 |